Cupping therapy for patients with chronic urticaria: A systematic review and meta-analysis  

作　　者：Xian-jun Xiao Lei-xiao Zhang Yun-zhou Shi Jun-peng Yao Wei Cao Ying Liu Zi-hao Zou Si-yuan Zhou Ming-ling Chen Chun-xiao Li Qian-hua Zheng Ying Li 

机构地区：[1]Acupuncture and Tuina School,Chengdu University of Traditional Chinese Medicine,Chengdu 610000,Sichuan Province,China [2]Rehabilitation Department,the People’s Hospital of Jianyang City,Chengdu 641400,Sichuan Province,China [3]Dermatological Department,Affiliated Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu 610000,Sichuan Province,China [4]Graduate School,Chengdu University of Traditional Chinese Medicine,Chengdu 610000,Sichuan Province,China

出　　处：《Journal of Integrative Medicine》2020年第4期303-312,共10页结合医学学报（英文版）

基　　金：supported by the National Key Research and Development Program of the China-Key Project“Research on Modernization of Traditional Chinese Medicine”——“International Cooperation Research on Evaluation of Acupuncture Advantage Diseases”(No.2017YFC1703600 and 2017YFC1703605)。

摘　　要：Background:Chronic urticaria(CU)is a common skin disease,which has a negative effect on quality of life.Current treatments do not fully control the symptoms of urticaria for many CU patients,thus effective and safe treatments for CU are still needed.Objective:This review aims to evaluate the effectiveness and safety of cupping therapy in patients with CU.Search strategy:The search strategy looked for the presence of related keywords,such as‘‘chronic urticaria"and‘‘cupping therapy,"in the title and abstract of research articles indexed in major databases.Randomized controlled trials(RCTs)were selected after querying nine electronic databases from their inception to May 2019 with the above search terms.Inclusion criteria:RCTs were included if they recruited patients with CU who were intervened with dry or wet cupping.Publications could be written in Chinese or English.Data extraction and analysis:Data were extracted,and the studies were assessed for the quality of their methodological design and risk of bias.Meta-analyses of the RCT data were conducted to assess the total effective rate of the treatment as the primary outcome.Skin disease quality of life index score,recurrence rate,and adverse events were assessed as secondary outcomes.Subgroup analyses were conducted based on different interventions.Results:Thirteen comparisons from 12 RCTs involving 842 participants were included.There were no significant differences between wet cupping and medications in total effective rate(n=372;risk ratio[RR]=1.10,95%confidence interval[CI]0.97 to 1.25;P=0.14)or recurrence rate(n=240;RR=0.56,95%CI 0.23 to 1.36;P=0.20).Cupping therapy,in combination with antihistamine treatment was more efficacious than antihistamines alone,with a greater total effective rate(n=342;RR=1.18,95%CI 1.01 to1.39;P=0.03)and lower recurrence rate(n=342;RR=0.52,95%CI 0.32 to 0.84;P=0.007).Cupping therapy combined with acupuncture was more effective than acupuncture alone(n=156;RR=1.25,95%CI 1.07 to 1.46;P=0.006).No serious adverse events were

关 键 词：CUPPING Chronic urticaria Systematic review META-ANALYSIS ANTIHISTAMINES ACUPUNCTURE 

分 类 号：R244.3[医药卫生—针灸推拿学]