雾化吸入3%高渗盐水治疗小儿毛细支气管炎效果及对肺功能影响  

Effect of aerosol inhalation of 3%hypertonic saline on bronchiolitis and pulmonary function in children

作　　者：李源斌 LI Yuan-bin(Department of Pediatrics,Xiaolan hospital,Southern Medical University,Guangdong Zhongshan 528415,China)

机构地区：[1]南方医科大学附属小榄医院儿科,广东中山528415

出　　处：《临床医药文献电子杂志》2020年第57期19-20,25,共3页Electronic Journal of Clinical Medical Literature

基　　金：中山市卫生局立项(编号:2019J241)。

摘　　要：目的探讨3%高渗盐水雾化吸入在小儿毛细支气管炎治疗中的疗效及其对患儿肺功能的影响。方法回顾分析2015年1月~2019年12月在我院住院确诊为毛细支气管炎的患儿61例,其中给干扰素、布地奈德、肾上腺素雾化等常规治疗为对照组(30例),在常规治疗基础上加用3%高渗盐水雾化吸入治疗的患儿为实验组共(31例),比较两组临床症状及肺部啰音消失时间、肺功能等差异。结果(1)实验组在咳嗽、喘息及肺部啰音消失时间均短于对照组,差异有统计学意义(P<0.05)。(2)治疗后两组肺功能指标TPTEF/TE和VPTEF/VE均较治疗前改善,且实验组优于对照组,差异有统计学意义(P<0.05)。结论雾化吸入3%高渗盐水治疗小儿毛细支气管炎效果明显,其有助于改善患儿肺功能。Objective To explore the effect of 3%hypertonic saline aerosol inhalation on treatment of children with bronchiolitis and its influence on the change of pulmonary function.Method A retrospective analysis of 61 children with bronchiolitis diagnosed in our hospital from January 2015 to December 2019 was made.Among them,A total of 30 children were given routine treatment such as interferon,budesonide and adrenaline atomization as the control group.On the basis of routine treatment,A total of 31 children who were treated with atomization inhalation of 3%hypertonic saline as the experimental group were compared with the control group in terms of disappearance time of clinical symptoms and disappearance time of lung rales and changes of lung function.Results(1)the disappearance time of cough,asthma and lung rales in the treatment group was significantly shorter than that in the control group(P<0.05).(2)The lung function indexes TPTEF/TE和VPTEF/VE of the two groups became better after treatment,especially in the experimental group(P<0.05).Conclusion Aerosol inhalation of 3%hypertonic saline is effective in the treatment of bronchiolitis in children,which is helpful to improve the pulmonary function of children with bronchiolitis.

关 键 词：高渗盐水 毛细支气管炎 肺功能 

分 类 号：R725.6[医药卫生—儿科]