脑胎盘率及主动脉峡部收缩指数评估晚发型胎儿生长受限妊娠结局  

Cerebroplacental ratio and aortic isthmus systolic index in evaluation on pregnancy outcome of late-onset fetal growth restriction

作　　者：徐平平 徐浩 XU Pingping;XU Hao(Department of Ultrasound,the Affiliated Xuzhou Maternity and Child Health Care Hospital of Xuzhou Medical University,Xuzhou 221009,China;Department of Interventional Radiology,the Affiliated Hospital of Xuzhou Medical University,Xuzhou 221006,China)

机构地区：[1]徐州医科大学附属徐州市妇幼保健院超声科,江苏徐州221009 [2]徐州医科大学附属医院介入放射科,江苏徐州221006

出　　处：《中国介入影像与治疗学》2020年第10期604-607,共4页Chinese Journal of Interventional Imaging and Therapy

基　　金：江苏省高校自然科学基金(18KJB310018)。

摘　　要：目的探讨脑胎盘率(CPR)及主动脉峡部收缩指数(ISI)对评价晚发型胎儿生长受限(FGR)妊娠结局的价值。方法回顾性分析88例经临床确诊的晚发型FGR孕妇,其中39例妊娠结局不良(病例组),49例妊娠结局良好(对照组),对比2组胎儿CPR及ISI,采用ROC曲线分析CPR、ISI对预测胎儿妊娠结局的价值。结果病例组CPR及ISI均小于对照组(P均<0.01)。ROC曲线结果显示,以1.25为CPR截断值,对不良妊娠结局预测的敏感度为82.1%,特异度为59.7%,AUC为0.814;以-0.44为ISI截断值,对不良妊娠结局预测敏感度为94.9%,特异度为82.7%,AUC为0.930。结论CPR及ISI对晚发型FGR胎儿不良妊娠结局均有预测价值,且ISI优于CPR。Objective To explore the value of cerebroplacental ratio(CPR)and aortic isthmus systolic index(ISI)in evaluation on pregnancy outcome of late-onset fetal growth restriction(FGR).Methods Totally 88 pregnant women with clinically confirmed late-onset FGR were retrospectively analyzed,among them 39 had poor pregnancy outcomes(case group)and 49 had good pregnancy outcomes(control group).CPR and ISI of fetuses were compared between 2 groups.ROC curve was used to analyze the value of CPR and ISI in predicting fetal pregnancy outcomes.Results CPR and ISI of case group were lower than those of control group(both P<0.01).ROC curve results showed that taken 1.25 as the cut-off value of CPR,the sensitivity and specificity of adverse pregnancy outcome was 82.1%and 59.7%,respectively,and AUC was 0.814;while taken-0.44 as the cut-off value of CPR,the sensitivity,specificity and AUC was 94.9%,82.7%and 0.930,respectively.Conclusion Both CPR and ISI had predictive value for fetal adverse pregnancy outcome of late-onset FGR,and ISI was superior to CPR.

关 键 词：胎儿发育迟缓 妊娠结局 超声检查 产前 脑胎盘率 主动脉峡部收缩指数 

分 类 号：R714.43[医药卫生—妇产科学] R445.1[医药卫生—临床医学]