Promotion Mechanism of H2O for Stereoselectivity in Pd(Ⅱ)-catalyzed C—H Aryiation of Diarylphosphinamides with Arylboronic Acids  

作　　者：CAI Yanchun JIAO Long QIU Xuepcng DU Zhijun 

机构地区：[1]Polymer Composites Engineering laboratory,Changchun Institute of Applied Chemistry,Chinese Academy of Sciences,Changchun 130022,P.R.China

出　　处：《Chemical Research in Chinese Universities》2020年第5期843-846,共4页高等学校化学研究（英文版）

基　　金：Supported by the National Natural Science Foundation of China(No.21772190).

摘　　要：On the basis of a series of control experiments and nuclear magnetic resonance analyses,it is discovered that Boc-protected amino acid ligand coordinated to Pd center is partly replaced by N,N-dimethylformamide,and H2O can inhibit coordination of N,N-dimethylformamide to Pd center.The novel action mechanism perfectly explains H2O promotion for stereoselectivity in Pd(II)-catalyzed C—H aryiation of diarylphosphinamides with arylboronic acids.

关 键 词：C-H activation STEREOSELECTIVITY WATER Ligand exchange 

分 类 号：O64[理学—物理化学]