Baeyer-Villiger Oxidation of Cyclic Ketones Catalyzed by Amino Acid Ionic Liquids  

作　　者：YU Fengli CHI Yujie GAO Chong CHEN Ruirui XIE Congxia YU Shitao 

机构地区：[1]State Key Laboratory Base of Eco-chemical Engineehng,College of Chemistry and Molecular Engineering,Qingdao University of Science and Technology,Qingdao 266042,P.R.China [2]College of Chemical Engineering,Qingdao University of Science and Technology,Qingdao 266042,P.R.China

出　　处：《Chemical Research in Chinese Universities》2020年第5期865-869,共5页高等学校化学研究（英文版）

基　　金：Supported by the National Natural Science Foundation of China(No.21878166);the Taishan Scholar Project of Shandong Province,China(No.ts201511033);the Emphasis Development Plan of Shandong Province,China(Nos.2017GGX70102,2017GGX40107);the Open Project of the Chemistry Department in Qingdao University of Science and Technology of China(No.QUSTHX201811).

摘　　要：A series of amino-acid-based ionic liquids was synthesized via one-step protonation of the corresponding L-amiiio acid by utilizing an array of proton sources.The catalytic activity of the amino-acid-based ionic liquids for the Baeyer-Villiger oxidation of cyclic ketones was investigated using cyclopentanone as a model cycloketone.Theproline-based ionic liquid[ProH]CF3SO3 was shown to exliibit thebest catalytic activity.The reaction condition was optimized to give the following reagent ratio of h(cyclopentanone):n(catalyst):w(H2O2)=1:0.06:4,60℃and 6 h.Under the optimum conditions,the conversion of cyclopentanone was 96.57%and the selectivity forδ-valerolactone was 73.01%.The catalytic activity was shown to be constant after 4 cycles.A simple treatment was allowed for the recover and the reuse of[ProH]CF3S03.The successful utilization of[ProH]CF3SO3 to catalyze a host of cyclic ketones via Baeyer-Villiger oxidation clearly demonstrated the capacity of[ProH]CF3S03 to tolerate variation in the substrate.

关 键 词：Amino acid ionic liquid Baeyer-Villiger oxidation Cyclic ketone LACTONE 

分 类 号：O62[理学—有机化学]