Effects of dietary valine supplementation during late gestation on the reproductive performance and mammary gland development of gilts  

作　　者：Long Che Mengmeng Xu Kaiguo Gao Li Wang Xuefen Yang Xiaolu Wen Hao Xiao Zongyong Jiang 

机构地区：[1]State Key Laboratory of Livestock and Poultry Breeding,Key Laboratory of Animal Nutrition and Feed Science in South China,Ministry of Agriculture,Guangdong Public Laboratory of Animal Breeding and Nutrition,Guangdong Key Laboratory of Animal Breeding and Nutrition,Institute of Animal Science,Guangdong Academy of Agricultural Sciences,No.1 Dafeng Street,Wushan Rd,Tianhe District,Guangzhou 510640,Guangdong,China [2]College of Animal Science and Technology,Henan University of Animal Husbandry and Economy,Zhengzhou 450046,Henan,China

出　　处：《Journal of Animal Science and Biotechnology》2020年第2期514-526,共13页畜牧与生物技术杂志（英文版）

基　　金：supported by The National Key Research and Development Program of China(2018YFD0501003);The Outstanding Talents Training Program of Guangdong Academy of Agricultural Sciences,China Agriculture Research System(CARS-35);Supporting Program for Guangdong Agricultural Research&Development Center of Livestock and Poultry Healthy Breeding.Operating Funds for Guangdong Provincial Key Laboratory of Animal Breeding and Nutrition(2014B030301054).

摘　　要：Background:Mammary gland development during late gestation in gilts is a major factor that alters the composition of colostrum and growth performance of piglets.Plasma valine is taken up and metabolized extensively by the mammary gland;however,the effects of valine on mammary gland development during late gestation are still unclear.Thirty primiparous gilts were divided into three treatment groups(n=10)and received one of the three diets starting on day 75 of gestation until the day of farrowing.The total dietary valine to lysine ratio of the three diets was 0.63(LV),0.73(MV),and 0.93(HV),respectively.Results:Dietary valine supplementation during late gestation did not affect(P>0.05)the litter size and weight at farrowing;however,the piglet weight and average daily gain at weaning were linearly increased(P<0.05)as the dietary valine increased.The highest piglet weight at weaning was observed when the gilts were provided the HV diet.Dietary valine supplementation linearly elevated(P<0.05)protein,fat and solids-not-fat and some free amino acids content in colostrum.The concentration of prolactin in plasma of gilts was linearly increased in response to valine supplementation at days 1 and 10 of lactation(P<0.05).Furthermore,with increasing dietary valine allowance,a linear increase(P<0.05)was observed in the area of the lumen of alveolus and the content of DNA,RNA,and total protein in the mammary tissues at day 1 of lactation.Moreover,the protein expression of cyclin D1,p-mTOR,p-S6,and p-4EBP1 was also linearly increased(P<0.05)in the mammary tissue at day 1 of lactation.However,no difference(P>0.05)was observed in the indices related to mammary development and the mTOR signaling pathway at day 21 of lactation.Conclusion:The results revealed that increasing the total dietary valine to lysine ratio to 0.93 during late gestation significantly enhances the piglet weight and average daily gain at weaning probably due to improved development of mammary gland.

关 键 词：GILT Mammary gland Piglet growth VALINE 

分 类 号：S828.5[农业科学—畜牧学]