Treatment of Infertile Women with Unilateral Tubal Occlusion Diagnosed by Hysterosalpingography:The Role of Intrauterine Insemination  

作　　者：Yi-hua LIN Jing-xin YE Ze-xuan WU Yun CHEN Xi XIA Wei-ping QIAN 

机构地区：[1]Department of Reproductive Center,Peking University Shenzhen Hospital,Shenzhen 518036,China [2]Department of Ultrasound,Peking University Shenzhen Hospital,Shenzhen 518036,China

出　　处：《Current Medical Science》2020年第4期767-772,共6页当代医学科学（英文）

基　　金：This study was supported by grants from the Research Team of Female Reproductive Health and Fertility Preservation(No.SZSM201612065);Project for Medical Discipline Advancement of Health and Family Planning Commission of Shenzhen Municipality(No.SZXJ2017003).

摘　　要：Summary:The optimal assisted reproductive treatment strategy for infertile women with unilateral tubal obstruction remains uncertain.To investigate the role of intrauterine insemination(IUI)in the treatment of infertile women with unilateral tubal occlusion,the data of 148 couples were retrospectively collected and analyzed.Seventy-eight infertile women with unilateral occlusion diagnosed by hysterosalpingography(HSG)were categorized as the study group and 70 others with unexplained infertility as the control group.The study group was divided into a proximal occlusion subgroup and a mid-distal occlusion subgroup for further analysis.The main outcomes,namely the clinical pregnancy rate(CPR),ongoing pregnancy rate(OPR),and live birth rate(LBR)per cycle,were analyzed.Our results showed a tendency of lower CPR,OPR,and LBR in the study group than in the control group,without statistical significance.Further investigations revealed that the unilateral proximal occlusion subgroup had similar CPR,OPR,and LBR as the control group,while the unilateral mid-distal occlusion subgroup had significantly lower CPR(5.1%vs.20.0%,P=0.035),OPR(5.1%vs.20.0%,P=0.035),and LBR(5.1%vs.20.0%,P=0.035)than the control group.In conclusion,the clinical outcomes of IUI were worse in patients with unilateral tubal occlusion than in those with unexplained infertility.This might be primarily caused by the worse outcome of patients with unilateral mid-distal tubal occlusion instead of proximal occlusion.

关 键 词：HYSTEROSALPINGOGRAPHY intrauterine insemination unilateral tubal factor infertility 

分 类 号：R71[医药卫生—妇产科学]