Intraosseous venous malformation of the maxilla after enucleation of a hemophilic pseudotumor: A case report  

作　　者：Xu Cai Jian-Jun Yu Hao Tian Zhen-Feng Shan Xiao-Yu Liu Jun Jia 

机构地区：[1]Department of Head&Neck Surgery,Hunan Cancer Hospital&The Affiliated Cancer Hospital of Xiangya School of Medicine,Central South University,Changsha 410000,Hunan Province,China [2]Physical Examination Center,The First Hospital of Changsha,Changsha 410000,Hunan Province,China [3]The State Key Laboratory Breeding Base of Basic Science of Stomatology(Hubei-MOST)and Key Laboratory of Oral Biomedicine Ministry of Education,School and Hospital of Stomatology,Wuhan University,Wuhan 430000,Hubei Province,China

出　　处：《World Journal of Clinical Cases》2020年第19期4644-4651,共8页世界临床病例杂志

基　　金：the Key Clinical Specialty Construction Project(Head and Neck Surgery)of Provincial Health Commission of Hunan Province.

摘　　要：BACKGROUND Hemophilic pseudotumor(HP)is a rare complication in patients with hemophilia.The lesion most frequently occurs in the long bones,pelvis,small bones of the hands and feet,or rarely in the maxillofacial region.Postoperative changes in HP are seldom arrested,whereas angiogenesis characterized by disturbed wound healing in HP may cause vascular malformations.CASE SUMMARY We report the case of an 11-year-old boy who was affected by maxillary intraosseous venous malformation.Enucleation of an HP without factor replacement was performed initially on the right side of the maxilla 3 years ago.The patient was referred to us because of painless swelling in the same location.Factor replacement and subtotal maxillectomy were performed.Pathological examinations revealed intraosseous venous malformation.CONCLUSION This study is the first to document the development of intraosseous venous malformation after enucleation of an HP in the maxillofacial region.Angiogenesis characterized by disturbed wound healing in patients with hemophilia may be pivotal in the pathogenesis of this condition.

关 键 词：HEMOPHILIA Hemophilic pseudotumor MAXILLA Venous malformation Angiogenesis Case report 

分 类 号：R782.23[医药卫生—口腔医学]