贵州兴仁某镇燃煤型砷中毒病区呼吸系统疾病年门诊人次的现况  

Current Situation of Annual Outpatient Visits for Respiratory Diseases in a Coal-Burning Arsenic Poisoning Area in a Town of Xingren,Guizhou

作　　者：阮璇 王文娟[2] 田宇 邹忠兰 杨敬源[2] 孙宝飞[2] 魏绍峰[2] 王大朋[2] 张爱华[2] RUAN Xuan;WANG Wenjuan;TIAN Yu;ZOU Zhonglan;YANG Jingyuan;SUN Baofei;WEI Shaofeng;WANG Dapeng;ZHANG Aihua(Central Health Center of Yuzhang Town,Xingren 562300,Guizhou,China;Key Laboratory for Environmental Pollution Monitoring and Disease Control of Ministry of Education&School of Public Health,Guizhou Medical University,Guiyang 550025,Guizhou,China)

机构地区：[1]雨樟镇中心卫生院,贵州兴仁562300 [2]贵州医科大学环境污染与疾病监控教育部重点实验室&公共卫生学院,贵州贵阳550025

出　　处：《贵州医科大学学报》2020年第10期1172-1175,1186,共5页Journal of Guizhou Medical University

基　　金：国家自然科学基金(U1812403,81872569,81430077)。

摘　　要：目的:了解贵州兴仁某镇燃煤砷暴露对呼吸系统疾病年门诊人次的影响,初步探讨和分析砷中毒病区居民呼吸系统疾病现况。方法:收集2018年贵州黔西南州兴仁某镇中心卫生院呼吸系统疾病每日门诊资料,根据《地方性砷中毒病区划分标准》(WS277-2007)将患者分为砷中毒组(5个砷中毒病区村)和非砷暴露组(6个非砷暴露村),按年龄、性别比较2组患者因呼吸系统疾病的门诊就诊人次数及发病人数,并采用二元Logistic回归模型进行多因素分析。结果:砷中毒组患者因呼吸系统疾患就诊人次构成比高于非砷暴露组,差异有统计学意义(χ2=80.8,P<0.001);按年龄分层,30~39岁、40~49岁、50~59岁、60~69岁及70~85岁年龄组砷中毒组患者因呼吸系统疾患就诊人次构成比均高于非砷暴露组(P<0.001);按性别分层,砷中毒组男性和女性患者因呼吸系统疾患就诊人次构成比均高于非砷暴露组(P<0.001);Logistic回归分析结果显示,砷中毒组患者因呼吸系统疾病就诊人次构成比增高的风险是非砷暴露组的1.26倍(OR=1.26,95%CI为1.18~1.35)。结论:砷暴露可增加患者呼吸系统疾病的风险,是引起呼吸系统疾病门诊量上升的原因之一。Objective:To evaluate impact of coal-burning arsenic exposure on annual outpatient visits for respiratory diseases in a town of Xingren in Guizhou Province,and explore and analyze the current situation of respiratory diseases among residents in arsenic poisoning area.Methods:The clinical information of daily outpatients for respiratory diseases was collected from the central health Center in Yuzhang town of Xingren,Qianxinan Prefecture,Guizhou Province in 2018.These patients were divided into arsenic-exposed group and non-arsenic-exposed group based on their living villages(5 arsenic poisoning area villages and 6 non-arsenic-exposed villages)according to Standard of Diagnosis for Endemic Arsenism(WS277-2007).The number of outpatients for respiratory diseases and the number of outpatients with respiratory diseases were compared by age and gender in the two groups,and a binary Logistic regression model was used for multivariate analysis.Results:The number of outpatients to examine respiratory diseases was greater in arsenic-exposed group than that in non arsenic-exposed group(χ2=80.8,P<0.001).The numbers of outpatient visits for respiratory diseases were higher in the age groups including 30~39,40~49,50~59,60~69 and 70~85 years old in the arsenic poisoning group than those in corresponding age groups in the non-arsenic exposure group(P<0.001).According to the sex stratification,the number of outpatient visits due to respiratory diseases was higher in both men and women in arsenic poisoning areas than those in non-arsenic exposure areas(P<0.001).Logistic regression analysis showed that patients had a higher risk in the arsenic poisoning group than those in non-arsenic poisoning group(OR=1.26,95%CI was 1.18~1.35).Conclusion:Arsenic exposure can increase the risk of patients with respiratory diseases,which is one of the reasons for the increase in the number of outpatients for respiratory diseases.

关 键 词：砷中毒 煤 呼吸系统 年龄组 门诊人次 性别 

分 类 号：R12[医药卫生—环境卫生学] R599.9[医药卫生—公共卫生与预防医学]