IL-17在动脉粥样硬化发病过程中的作用  

Role of IL-17 in pathogenesis of atherosclerosis

作　　者：于洋[1] 田晓彦[1] 郑艳贺 沈岩[1] YU Yang;TIAN Xiao-yan;ZHENG Yan-he;SHEN Yan(Department of Neurology,Forth Affiliated Hospital of Harbin Medical University,Harbin,Heilongjiang,150001,China)

机构地区：[1]哈尔滨医科大学附属第四医院神经内科,黑龙江哈尔滨150001

出　　处：《心血管康复医学杂志》2020年第5期615-618,共4页Chinese Journal of Cardiovascular Rehabilitation Medicine

基　　金：黑龙江省卫生厅科研课题(2010-137)。

摘　　要：免疫细胞及其介质直接引起的慢性动脉炎症是动脉粥样硬化(AS)的特点,白细胞介素(IL)-17是主要促炎性细胞因子。近年来,关于IL-17在AS中的多效性及其功能的探讨逐渐深入。本文就IL-17在AS中的作用的相关研究作一综述,旨在为研究AS的发生发展机制提供新思路。Chronic arterial inflammation directly caused by immune cells and their mediators is a characteristic of atherosclerosis,and interleukin(IL)-17 is the main pro-inflammatory cytokine.In recent years,exploration on pluripotency of IL-17 in AS and its function is gradually deepening.The present article made a review on related researches about role of IL-17 in AS,aimed to provide new thinking for studying the occurrence and development mechanism of AS.

关 键 词：动脉粥样硬化 白细胞介素17 T淋巴细胞 

分 类 号：R543.509[医药卫生—心血管疾病]