2016-2019年吉林省MSM人群HIV-1新发感染率分析  

The analysis of HIV-1 recent infection rate among men who have sex with men in Jilin province from 2016 to 2019

作　　者：郭琪[1] 臧希卉[1] 吴东林[1] 杨显达[1] 柳洪敏 武月婷 GUO Qi;ZANG Xi-hui;WU Dong-lin;YANG Xian-da;LIU Hong-min;WU Yue-ting(Department of Virus Disease Prevention and Control,Jilin Provincial Center for Disease Control and Prevention,Changchun Jilin 130062,China)

机构地区：[1]吉林省疾病预防控制中心病毒所,吉林长春130062

出　　处：《中国卫生工程学》2020年第5期663-666,共4页Chinese Journal of Public Health Engineering

基　　金：吉林省卫生计生自筹经费课题(2015ZC033)。

摘　　要：目的了解吉林省2016-2019年MSM人群(男男性行为人群)HIV-1新发感染情况。方法应用限制性抗原亲和力酶免法(limiting antigen avidity enzyme immunoassay,LAg-avidity EIA,简称LAg)检测2016-2019年吉林省MSM人群哨点监测样本,分别为1210例、1220例、1210例和1220例,估计本省MSM人群HIV-1新发感染率及流行趋势;结合MSM调查问卷中人口学特征及梅毒血清学结果进行危险因素分析。结果4年间总新发感染率为0.88%,分别为3.64%、4.86%、0.00%和0.99%。不同年度间年龄、婚姻状况、文化程度、知识知晓、行为和血清学检测差异均有统计学意义(均P<0.05)。单因素分析结果表明,新发感染组与非新发感染组间肛交性行为时使用安全套的频率、梅毒检测结果和肛交行为次数比较差异均有统计学意义(均P<0.05)。多因素分析结果表明,肛交性行为时使用安全套的频率、梅毒检测结果和肛交行为频次是HIV-1新发感染的独立危险因素(均P<0.05)。结论针对吉林省MSM人群艾滋病疫情严重,应采取相应干预措施,科学有效地控制该人群的新发感染率。Objective To understand the status of HIV-1 recent infection among men who have sex with men in Jilin from 2016 to 2018.Methods 1210,1220 and 1210 samples of three MSM sentinel sites were collected and detected with LAg method to evaluate the recent infection rate and prevalent trends,and questionnaires including demographic characteristics and the results of syphilis serology were combined to analyze the risk factors.Results The total recent infection rate was 0.88%,3.64%,4.86%,0%and 0.99%respectively.There were statistically significant among ages,maritalstatus,culture degree,knowledge awareness rate,behavior style and serological test in four different years(P<0.05).There were statistically significant in use frequency of condom of anal sex,syphilis results and times of anal sex between recent infection group and non-recent infection group in single-factor analysis.Frequency of condom use during anal sex,syphilis test results and frequency of anal sex were the independent risk factor of HIV-1 recent infection in multiple-factor analysis.Conclusion According to the severity of epidemic among MSM in Jilin,related intervene measurements should be adopted in order to control the recent infection rate among MSM scientifically and effectively.

关 键 词：吉林省 MSM HIV-1新发感染率 

分 类 号：R512.91[医药卫生—内科学]