性激素周期疗法联合补肾调经中药分期治疗月经过少临床研究  

Clinical Study on Periodic Therapy of Sex Hormones Combined with Chinese Herbal Medicine of Tonifying the Kidney and Regulating Menstruation by Stages for Hypomenorrhea

作　　者：马素敏 MA Sumin

机构地区：[1]濮阳市妇幼保健院中医妇科,河南濮阳457000

出　　处：《新中医》2020年第19期102-104,共3页New Chinese Medicine

摘　　要：目的:观察性激素周期疗法联合补肾调经中药分期治疗月经过少的临床疗效。方法:将月经过少患者130例随机分为对照组与观察组,各65例。对照组应用性激素周期疗法治疗,观察组在对照组的基础上,根据月经周期应用补肾调经中药治疗。观察2组治疗前后月经量、行经周期及中医证候积分变化,检测2组治疗前后血清促卵泡生成素(FSH)、促黄体生成素(LH)、雌二醇(E2)水平,统计2组总体临床疗效。结果:总有效率观察组为95.4%,对照组为81.5%,2组比较,差异有统计学意义(P<0.05)。治疗后,2组患者月经量均较治疗前增加、行经时间较治疗前延长,差异均有统计学意义(P<0.05);且观察组两项指标改善较对照组更显著(P<0.05)。治疗后,2组头晕耳鸣、腰膝酸软、小腹坠胀等中医证候积分均较治疗前明显减少(P<0.05);且观察组各项积分明显低于对照组(P<0.05)。治疗后,2组血清FSH、LH、E2水平圴较治疗前明显升高(P<0.05),且观察组各项指标明显高于对照组(P<0.05)。结论:根据月经周期应用补肾调经中药联合性激素周期疗法治疗月经过少,可明显增加月经量,延长行经周期,改善血清性激素水平。Objective:To observe the clinical effect of periodic therapy of sex hormones combined with Chinese herbal medicine of tonifying the kidney and regulating menstruation by stages for hypomenorrhea. Methods:A total of 130 cases of patients with hypomenorrhea were randomly divided into the control group and the observation group, 65 cases in each group. The control group was treated with periodic therapy of sex hormones, and the observation group was additionally treated with Chinese herbal medicine of tonifying the kidney and regulating menstruation according to menstrual cycle based on the treatment of the control group. Before and after treatment,the changes in menstrual amount,menstrual cycles and Chinese medicine syndrome scores in the two groups were observed,and the levels of follicle stimulating hormone(FSH),luteinizing hormone(LH) and estrogen(E2) in serum in the two groups were detected. The total clinical effect in the two groups was counted. Results: The total effective rate was 95.4% in the observation group and 81.5% in the control group, the difference being significant(P<0.05). After treatment, the menstrual amount in the two groups was increased when compared with that before treatment, and the menstrual duration was prolonged, differences being significant(P<0.05);the improvement of the above two indexes in the observation group was more significant than that in the control group(P<0.05). After treatment, the Chinese medicine syndrome scores including dizziness, tinnitus, soreness and weakness of waist and knees and downbearing distention in lower abdomen in the two groups were significantly decreased when compared with those before treatment(P<0.05);the scores in the observation group were significantly lower than those in the control group(P<0.05). After treatment, the levels of FSH, LH and E2 in serum in the tow groups were significantly increased when compared with those before treatment(P<0.05);the scores in the observation group were significantly higher than those in the control group(P<0.05)

关 键 词：月经过少 性激素周期疗法 补肾调经 分期治疗 

分 类 号：R711.51[医药卫生—妇产科学]