新型冠状病毒肺炎患者的临床特征及影响因素分析  

An analysis of clinical features and influencing factors of patients with new coronavirus pneumonia

作　　者：余宏伟 辛士珍[2] 梅早仙[1] YU Hongwei;XIN Shizhen;MEI Zaoxian(Department of Tuberculosis,Tianjin Haihe Hospital(Tianjin Institute of Respiratory Diseases),Tianjin 300000,CHINA)

机构地区：[1]天津市海河医院(天津市呼吸疾病研究所)结核科,300000 [2]天津市海河医院(天津市呼吸疾病研究所)营养科,300000

出　　处：《江苏医药》2020年第9期904-907,912,共5页Jiangsu Medical Journal

摘　　要：目的分析129例新型冠状病毒肺炎(COVID-19)患者的临床特征,探讨影响病情的危险因素。方法回顾性分析129例COVID-19患者的临床资料。结果129例患者中,发热116例(89.92%),无临床症状4例(3.10%)。96.89%的患者出现靠近外周的斑片磨玻璃影;其中,双肺受累患者72.09%。129例患者中,轻型/普通型患者76例,重型/危重型53例。接受有创机械通气5例,接受体外膜肺氧合治疗2例。病死率2.20%。多因素logistic回归分析显示,BMI、年龄、入院时白蛋白水平和淋巴细胞计数是病情严重程度的影响因素。结论COVID-19患者主要临床表现有发热,影像学表现以靠近外周为主的斑片影、磨玻璃影多见,多数患者双肺受累。年龄大和BMI指数高是发生危重症COVID-19的危险性因素;淋巴细胞数和白蛋白水平高是COVID-19保护性因素。Objective To analyze the clinical characteristics of 129 patients with coronavirus disease 2019(COVID-19)and the risk factors affecting the illness status.Methods The clinical data of 129 patients with COVID-19 were analyzed retrospectively.Results Of 129 patients with COVID-19,116(89.92%)cases had a history of fever,4 cases(3.10%)were without clinical symptoms.Plaque gross glass-like manifestation near the periphery was seen in 96.89%of the patients,of which 72.09%had bilateral lung involvement.Of 129 patients,76 cases were the light or common cases and 53 cases were the severe or critical cases.Five patients received invasive mechanical ventilation and two cases received ECMO treatment.The mortality was 2.20%.Multivariate logistic regression analysis showed that BMI,age,albumin level at admission,and lymphocyte count were the factors influencing the severity of the disease.Conclusion Fever is the main clinical feature of patients with COVID-19 and the imaging findings are mainly patchy shadows and gross glass-like change near the periphery.Most patients have bilateral lung involvement.Older age and high BMI are the risk factors for severe cases and lymphocyte count and albumin level are the protective factors for COVID-19.

关 键 词：新型冠状病毒肺炎 

分 类 号：R512[医药卫生—内科学]