光介导抗菌涂层的研究进展  

Research progress on light-mediated antibacterial coatings

作　　者：姚添甜 李熇阳 任科峰[1] 计剑[1] YAO Tiantian;LI Heyang;REN Kefeng;JI Jian(MOE Key Laboratory of Macromolecule Synthesis and Functionalization,Department ofPolymer Science and Engineering,Zhejiang University,Hangzhou 310027,China)

机构地区：[1]浙江大学高分子科学与工程学系,教育部高分子合成与功能构造重点实验室,杭州310027

出　　处：《功能材料》2020年第10期10036-10043,共8页Journal of Functional Materials

基　　金：国家重点研发计划资助项目(2017YFB0702500);国家自然科学基金资助项目(21875210)。

摘　　要：植/介入医疗装置引起的细菌感染是医源性感染的重要组成部分,严重危害病人生命健康,同时造成了巨大的社会经济损失。在医疗装置表面构建抗菌涂层是预防和解决医源性感染最有效和最实用的方法之一。光介导的抗菌涂层利用光照实现细菌灭活,具有灵活可控和不易引起细菌耐药性的优势,得到研究人员的广泛关注。本文介绍了基于光介导的抗菌涂层的作用机制、研究进展以及发展趋势,对该领域未来的研究进行了展望。Bacterial infections caused by implanted/interventional medical devices have become the main component of health care-associated infection(HAI),threatening the health of patients and causing huge economic losses.Construction of antibacterial coating on the surface of medical devices is one of the most effective and practical methods to prevent and inhibit HAI.Light-mediated antibacterial coatings,which use light irradiation to inactivate bacteria,are flexible and controllable,and won t cause bacterial resistance.Those advantages have attracted extensive attention.In this paper,the mechanism,research progress and development trend of light-mediated antibacterial coatings were summarized.

关 键 词：光介导策略 抗菌涂层 光热抗菌 光动力抗菌 植介入医用装置 医源性感染 

分 类 号：TB34[一般工业技术—材料科学与工程]