经阴道三维超声联合抗苗勒氏激素评估卵巢储备功能的价值  

Value of transvaginal three-dimensional ultrasound combined with anti-Mullerian hormone level for evaluating ovarian reserve function

作　　者：邵瑾 SHAO Jin(Changxing Maternal and Child Health Care Hospital,Zhejiang Province,313100)

机构地区：[1]浙江省长兴县妇幼保健院,313100

出　　处：《中国计划生育学杂志》2020年第10期1613-1616,共4页Chinese Journal of Family Planning

摘　　要：目的:分析经阴道三维超声联合抗苗勒氏激素(AMH)检测评估卵巢储备功能价值。方法:回顾性收集2017年4月-2019年6月于本院行孕前检查的120例妇女,按检测结果卵巢储备功能分为早衰组、减退组和对照组,比较各组经阴道三维超声检查参数、性激素和AMH水平,分析各指标相关性及诊断卵巢储备功能价值。结果:早衰组、减退组、对照组卵泡刺激素(FSH)、黄体生成素(LH)水平依次递减(P<0.05),孕酮(P)及泌乳素(PRL)水平各组比较无差异(P>0.05)。早衰组、减退组、对照组超声参数窦卵泡(AFC)数量、卵巢血管指数(VI)、血管血流指数(VFI)、血流指数(FI),以及AMH水平均呈依次递增(P<0.05)。超声参数AFC、OV、VI、FI和VFI与AMH水平均呈正相关性(P<0.05)。超声与AMH联合检测诊断卵巢储备功能时的灵敏度(94.4%)、特异度(87.7%)及准确度(90.4%)均高于超声及AMH单独应用(P<0.05)。结论:经阴道三维超声与AMH联合诊断对卵巢储备功能有良好的评估价值。Objective: To analyze the value of transvaginal three-dimensional ultrasound(TTDU) combined with anti-Mullerian hormone(AMH) level for evaluating ovarian reserve function. Methods: 120 women who underwent prenatal examination from April 2017 to June 2019 were collected retrospectively and were divided into group A(women with premature ovarian failure), group B(women with ovarian reserve function decreases), and group C(women with normal ovarian reserve function) according to ovarian reserve function(ORF). The parameters by TTDU, and the levels of sex hormone and AMH of women were compared among the three groups. The correlation between ultrasound parameters and AMH and sex hormone levels, and their values for diagnosing ORF were analyzed. Results: The level of FSH or LH of women in group A was the highest, but that of women in group C was the lowest(P<0.05. There were no significant different in P and PRL levels of women among the three groups(P<0.05).There was no significant difference in P and PRL levels among groups(P>0.05). The ultrasound parameter, such as AFC, or the value of OV,VI,FI or VFI, or AMH level of women in group A was the lowest, but that of women in group C was the highest(P<0.05). AFC, and the values of OV, VI, FI and VFI were positively correlated with AMH level(P<0.05). The sensitivity, the specificity, and the accuracy of ultrasound parameters combined with MAH level for evaluating ORF were 94.4%, 87.7%, and 90.4%, respectively, which were significant superior to those of ultrasound parameter or MAH level alone(P<0.05). Conclusion: The ultrasound parameters by TTDU combined with MAH level for evaluating ORF has good value.

关 键 词：卵巢储备功能 经阴道三维超声 抗苗勒氏激素 性激素 

分 类 号：R711.75[医药卫生—妇产科学]