子宫内膜息肉微创手术对自然妊娠的影响因素分析  

Analysis of the influence of minimally invasive surgery for treating women with endometrial polyp on their later natural pregnancy

作　　者：高勇 贺晓琪 黄艳丽[3] 刘韵[3] GAO Yong;HE Xiaoqi;HUANG Yanli;LIU Yun(Honghu Hospital,Hubei Province,433200;Union Hospital affiliated to Tongji Medical College,Huazhong University of Science and Technology;Xiangyang Central Hospital,Affiliated Hospital of Hubei College of Arts and Science)

机构地区：[1]湖北省洪湖市人民医院,433200 [2]华中科技大学同济医学院附属协和医院 [3]湖北省襄阳市中心医院,湖北文理学院附属医院

出　　处：《中国计划生育学杂志》2020年第10期1680-1684,共5页Chinese Journal of Family Planning

摘　　要：目的:观察子宫内膜息肉(EP)微创手术后自然妊娠影响因素。方法:回顾性分析2017年2月-2019年2月本院妇科收治的63例行微创手术治疗的EP患者临床资料,收集患者围手术期相关指标、术后相关情况;1年随访结束后根据受孕情况分为妊娠组(n=40)和未妊娠组(n=23),比较两组年龄、体质指数(BMI)、不孕年限、病程、遗传史、糖尿病病史、高血压病史、息肉部位、息肉侧别、既往宫腔操作史、息肉数量、术后激素用药、术中出血量、住院时间、息肉大小、心率(RR)、白细胞计数(WBC)、血小板(PLT)、体温(T)、平均动脉压(MAP),logistic回归分析影响自然妊娠危险因素。结果:63例患者成功完成手术和随访;手术时间32.0±8.2min、术中出血量50.2±15.3ml、住院时间3.6±1.0d、术后引流量25.0±8.5ml;术后阴道出血2例(3.17%),EP复发1例(1.6%),自然妊娠40例(63.5%);息肉部位、息肉数量、术后激素用药、年龄、BMI、不孕年限、病程等是影响EP术后患者自然妊娠的因素(P<0.05)。结论:临床早期治疗时可改善患者子宫功能,以提高术后自然妊娠率。Objective: To investigate the influence of minimally invasive surgery for treating women with endometrial polyp(EP) on their later natural pregnancy. Methods: The clinical data of 63 women with EP treated by minimally invasive surgery from February 2017 to February 2019 were retrospectively analyzed. Relevant perioperative indicators and postoperative conditions of women were collected. Postoperative 1 year followed up, these women were divided into two groups according to their natural pregnancy state, which included 40 women with pregnancy in group A and 23 women without pregnancy in group B. Age, body mass index(BMI), infertility duration, course of disease, genetic history, history of diabetes, history of hypertension, polyp size, respiratory frequency(RR), white blood cell count(WBC), Platelet(PLT), temperature(T), and mean arterial pressure(MAP)previous uterine cavity of women were compared between the two groups. Logistic regression analysis was used to analyze the risk factors of natural pregnancy. Results: All women in the two groups had completed the operation and followed up successfully. The operation time, intraoperative bleeding volume, hospital stay time, postoperative drainage volume of all women were 32.02±8.2 min, 210.2±15.3 ml, 3.6±1.0 d, and 25.0±8.5 ml, respectively. There were 2(3.17%) cases with postoperative vaginal bleeding, 1 case(1.6%) with EP recurrence, and 40(63.5%) cases with natural pregnancy. The site and number of polyp, postoperative hormone medication, age, BMI, infertility duration, and course of disease were the influencing factors of postoperative natural pregnancy of women with EP(P<0.05). Conclusion: Early treatment of women with EP can improve their uterine function and natural pregnancy rate.

关 键 词：子宫内膜息肉 微创手术 自然妊娠 影响因素 

分 类 号：R713.4[医药卫生—妇产科学]