铜绿假单胞菌性角膜炎发病机制的研究进展  

Research progress on the pathogenesis of pseudomonas aeruginosa keratitis

作　　者：王岚 李妍[1] 孙子雯 胡竹林[1] Lan Wang;Yan Li;Zi-Wen Sun;Zhu-Lin Hu(Department of Ophthalmology, Fourth Affiliated Hospital of Kunming Medical University, the Second People's Hospital of Yunnan Province, Yunnan Eye Institute, The Ocular Disease and Clinical Medicine Research Center of Yunnan Province, The Ocular Disease Clinical Medicine Center of Yunnan Province, Key Laboratory of Yunnan Province for the Prevention and Treatment of Ophthalmology, Provincial Innovation Team for Cataract and Ocular Fundus Disease, the Second People's Hospital of Yunnan Province, Kunming 650021, Yunnan Province, China)

机构地区：[1]昆明医科大学第四附属医院眼科,云南省第二人民医院眼科,云南省眼科研究所,云南省眼部疾病临床医学研究中心,云南省眼病临床医学中心,云南省眼科疾病防治研究重点实验室,云南省第二人民医院白内障与眼底疾病防治省创新团队,云南省昆明市650021

出　　处：《国际眼科杂志》2020年第11期1916-1919,共4页International Eye Science

基　　金：云南省基础研究计划(昆医联合专项)[No.2018FE001(-265)]。

摘　　要：铜绿假单胞菌性角膜炎是临床上常见的角膜炎之一,其起病急、发展迅速,并且治疗棘手。若未及时治疗,极易形成角膜溃疡,严重时可致盲。为增加有效治疗的手段,深入研究其发病机制有重要意义。本文就铜绿假单胞菌的致病性与宿主的免疫反应在铜绿假单胞菌性角膜炎的发病机制中所起的作用进行了概述,以期为其治疗的新`思路提供理论依据`。Pseudomonas aeruginosa keratitis can be described as one of the most common keratitis in clinical practice.It is characterized by an acute onset,fast development and hard to be treated entirely.Once failed to get prompt treatment,it would cause corneal ulcer,in an extreme case,blindness.In order to enhance the probability of treatment,it is meaningful to study the pathogenesis of pseudomonas aeruginosa keratitis further.The article reviews the pathogenicity of pseudomonas aeruginosa,and how the immunoreaction of host works in the pathogenesis of pseudomonas aeruginosa keratitis,thereby to provide theoretical basis of new methods for the treatment of pseudomonas aeruginosa keratitis.

关 键 词：角膜炎 铜绿假单胞菌 发病机制 

分 类 号：S85[农业科学—兽医学]