苯巴比妥在重度新生儿窒息中的应用效果  

Application effect of phenobarbital in severe neonatal asphyxia

作　　者：刘佳 LIU Jia(Department of Pediatrics,Jinzhou Maternal and Infant Hospital,Jinzhou 121000,China)

机构地区：[1]锦州市妇婴医院儿科,121000

出　　处：《中国现代药物应用》2020年第20期139-141,共3页Chinese Journal of Modern Drug Application

摘　　要：目的分析在重度新生儿窒息的治疗中应用苯巴比妥对患儿各项指标及疗效的影响。方法102例重度新生儿窒息患儿,依据随机数字表法分为对照组与观察组,各51例。对照组施行常规治疗,观察组在对照组基础上服用苯巴比妥。对比两组患儿治疗后的各项指标及临床疗效。结果观察组患儿的呼吸、肌张力及拥抱反射恢复时间分别为(2.11±0.45)、(1.01±0.26)、(1.08±0.28)d,均短于对照组的(5.36±0.65)、(2.46±0.57)、(3.32±0.54)d,差异具有统计学意义(P<0.05)。观察组治疗总有效率96.08%,明显高于对照组的74.51%,差异具有统计学意义(P<0.05)。结论将苯巴比妥药物应用在重度新生儿窒息的治疗中,能有效帮助患儿恢复各项功能指标,促进患儿疾病治愈,在临床中推行实施的价值较大。Objective To analyze the influence of phenobarbital on various indexes and curative effects of neonates with severe asphyxia.Methods A total of 102 neonates with severe asphyxia were divided into control group and observation group according to random numerical table,with 51 cases in each group.The control group was treated with conventional therapy,and the observation group was treated with phenobarbital on the basis of the control group.The indexes after treatment and clinical efficacy were compared between the two groups.Results The recovery time of respiration,muscle tone and hugging reflex of the observation group were(2.11±0.45),(1.01±0.26)and(1.08±0.28)d,which were shorter than(5.36±0.65),(2.46±0.57)and(3.32±0.54)d of the control group,and the difference was statistically significant(P<0.05).The total effective rate of treatment 96.08%of the observation group was obviously higher than 74.51%of the control group,and the difference was statistically significant(P<0.05).Conclusion The application of phenobarbital during the treatment of severe neonatal asphyxia can effectively help children restore various functional indicators and promote the cure of children.It is of greater value in clinical implementation.

关 键 词：苯巴比妥 重度新生儿窒息 临床疗效 

分 类 号：R722.12[医药卫生—儿科]