三黄散对自身免疫性大疱性皮肤病创面感染防治研究  

Study on the Prevention and Treatment of Sanhuang San on Autoimmune Bullous Skin Disease Wound Infection

作　　者：曾彬[1] 李元元 邬晶 黎敏[1] Zeng Bin;Li Yuanyuan;Wu Jing;Li Min

机构地区：[1]重庆市中医院皮肤科,重庆400011

出　　处：《实用中医药杂志》2020年第10期1252-1253,共2页Journal of Practical Traditional Chinese Medicine

基　　金：重庆市卫生计生委中医药科技项目(ZY201702015)。

摘　　要：目的:观察外用三黄散对自身免疫性大疱性皮肤病创面细菌感染(包括多重耐药菌感染)的防治作用。方法:74例根据创面是否合并细菌感染分为A组(感染组30例)、B组(非感染组44例),采用自身对照法,在同一患者身上选取两组面积、位置相近的创面,分为研究组、对照组。研究A组、B组外用三黄散,对照A组外用夫西地酸乳膏,对照B组不用药物。结果:研究A组、B组总有效率分别为90%、97.7%,对照A组、B组总有效率分别为80%、90.9%,研究组与对照组比较差异有统计学意义(P<0.05)。结论:三黄散能防治自身免疫性大疱性皮肤病创面感染。Objective:To observe the prevention and treatment effect of topical Sanhuang San on autoimmune bullous skin disease wounds with bacterial infections(including multi-drug resistant bacteria infections).Method:74 cases were divided into group A(30 cases in the infected group)and group B(44 cases in the non-infected group)according to whether the wounds were complicated by bacterial infection.The self-control method was used to select two groups of wounds with similar area and location on the same patient.They were divided into study group and control group.The study group A and the study group B were treated with Sanhuang San by external application.T he control group A was treated with fusidic acid cream by external application while the control group B did not use any drugs.Result:The total effective rate of the study group A and B was 90%and 97.7%respectively while the total effective rates of the control group A and B was 80%and 90.9%respectively.The difference between the study group and the control group was statistically significant(P<0.05).Conclusion:Sanhuang San could prevent and treat wound infections of autoimmune bullous skin diseases.

关 键 词：大疱性皮肤病 三黄散 创面感染 

分 类 号：R275.932.9[医药卫生—中西医结合]