乙酰半胱氨酸溶液雾化吸入和氨溴素静脉滴注治疗肺炎支原体肺炎的疗效比较分析  

Comparative analysis of the efficacy of atomization inhalation of acetylcysteine solution and intravenous drip of ambroxol on mycoplasma pneumoniae pneumonia

作　　者：张迪 ZHANG Di(The First Hospital of Xuzhou Coal Mining Group,Jiangsu,Xuzhou 221131,China)

机构地区：[1]江苏省徐州矿务集团第一医院,江苏徐州221131

出　　处：《中国医药科学》2020年第17期115-117,142,共4页China Medicine And Pharmacy

摘　　要：目的探讨乙酰半胱氨酸溶液雾化吸入和氨溴素静脉滴注治疗肺炎支原体肺炎的疗效比较情况。方法选取徐州矿务集团第一医院儿科2019年9月~2020年3月收治的肺炎支原体肺炎患儿60例作为研究对象,依据治疗方式不同分为氨溴索静滴组(30例)和乙酰半胱氨酸组(30例)。观察两组患儿退热时间、咳嗽消失时间、喉中痰鸣消失时间、住院时间、临床疗效、不良反应发生情况。结果乙酰半胱氨酸组患儿退热、咳嗽消失、喉中痰鸣消失、住院时间均短于氨溴索静滴组,乙酰半胱氨酸组患儿临床总有效率高于氨溴索静滴组,差异均有统计学意义(P <0.05)。两组患儿不良反应总发生率比较,差异无统计学意义(P> 0.05)。结论乙酰半胱氨酸溶液雾化吸入治疗肺炎支原体肺炎患儿,临床症状改善明显,效果良好,值得临床推广应用。Objective To investigate the comparison of the efficacy of atomization inhalation of acetylcysteine solution and intravenous drip of ambroxol on Mycoplasma pneumoniae pneumonia.Methods From September 2019 to March 2020,60 children with Mycoplasma pneumoniae pneumonia admitted to the department of pediatrics of the first hospital of Xuzhou coal mining group were selected as research objects,and were divided into the ambroxol intravenous drip group(n=30)and the acetylcysteine group(n=30)according to different treatment methods.The antipyretic time,cough disappearance time,phlegm in throat disappearance time,hospitalization time,clinical efficacy and adverse reactions of the two groups were observed.Results The antipyretic time,cough disappearance time,phlegm in throat disappearance time and hospitalization time of children in the acetylcysteine group were shorter than those in the ambroxol intravenous drip group.The total clinical efficacy rate of children in the acetylcysteine group was higher than that in the ambroxol intravenous drip group,and the difference was statistically significant(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion Atomization inhalation of acetylcysteine solution in the treatment of children with Mycoplasma pneumoniae pneumonia has obvious improvement in clinical symptoms and good efficacy,which is worthy of clinical promotion and application.

关 键 词：乙酰半胱氨酸溶液 雾化吸入 氨溴素 静脉滴注 肺炎支原体肺炎 

分 类 号：R725.6[医药卫生—儿科]