穴位注射辅助治疗单纯疱疹病毒性角膜炎恢复期干眼疗效观察  

Therapeutic effect of acupoint injection as adjuvant treatment on dry eyes of convalescent herpes simplex keratitis

作　　者：张光红 李小玉 李杜军[1,2] 吴克虎 吴琳[3] 罗继红 ZHANG Guang-hong;LI Xiao-yu;LI Du-jun;WU Ke-hu;WU Lin;LUO Ji-hong(Department of Ophthalmology,Hubei Provincial Hospital of TCM,Wuhan 430061,China;Department of Ophthalmology,Hubei Province Academy of TCM,Wuhan 430074,China;Department of Ophthalmology,Central China Normal University Hospital)

机构地区：[1]湖北省中医院眼科,武汉430061 [2]湖北省中医药研究院眼科,武汉430074 [3]华中师范大学医院眼科

出　　处：《中国针灸》2020年第10期1081-1084,共4页Chinese Acupuncture & Moxibustion

基　　金：湖北省中医院“五专”建设项目:鄂中医院字[2018]64号。

摘　　要：目的:评价穴位注射鱼腥草辅助治疗单纯疱疹病毒性角膜炎(HSK)恢复期干眼的临床疗效。方法:将60例HSK恢复期干眼患者随机分为观察组和对照组,每组30例。对照组采用人工泪液联合抗炎药治疗;观察组在对照组治疗基础上联合内球后穴注射鱼腥草治疗,每次3 mL,每日1次,连续3次,之后调整为隔日1次,连续3次,6次为一疗程,共治疗1个疗程。观察并分析两组患者治疗前及治疗后7、15、30 d视觉模拟量表(VAS)评分、基础泪液分泌试验(SⅠT)、泪膜破裂时间(BUT)以及角膜荧光素染色(CFS)评分的变化。结果:治疗后7、15、30 d两组患者VAS评分、CFS评分均较治疗前降低(P<0.05),且观察组VAS评分、CFS评分低于对照组(P<0.05);治疗后7、15、30 d,两组患者SⅠT、BUT均较治疗前升高(P<0.05),且治疗后15、30 d观察组SⅠT、BUT高于对照组(P<0.05)。结论:穴位注射鱼腥草辅助治疗HSK恢复期干眼可促进角膜上皮恢复,减轻不适症状,同时可增加泪液分泌和泪膜的稳定性。Objective To evaluate the clinical effect of acupoint injection of houttuynia cordata as the accessory treatment on dry eyes of convalescent herpes simplex keratitis(HSK).Methods A total of 60 patients with dry eyes of convalescent HSK were randomized into an observation group and a control group,30 cases in each one.In the control group,the artificial tears and anti-inflammatory drugs were combined in treatment.In the observation group,on the base of the treatment as the control group,the acupoint injection of houttuynia cordata at Neiqiuhou(Extra)was combined,3 mL each time,once a day.After consecutive 3 injections,the injection was adjusted to be once every two days,consecutively for 3 times.The treatment for 6 times was as one course and one course of treatment was required.Separately,before treatment and in 7,15 and 30 days after treatment,the changes of the scores of visual analogue scale(VAS),the results of SchirmerⅠtest(SⅠT),the tear break-up time(BUT)and the score of corneal fluorescein staining(CFS)were observed and analyzed in the patients of the two groups.Results In 7,15 and 30 days after treatment,VAS scores and CFS scores were all reduced as compared with those before treatment in the patients of the two groups(P<0.05),and the scores of VAS and CFS in the observation group were lower than those in the control group(P<0.05).In 7,15 and 30 days after treatment,the values of SⅠT and BUT were all increased as compared with those before treatment in the patients of the two groups(P<0.05),and the values in the observation group were higher than the control group in 15 and 30 days after treatment(P<0.05).Conclusion Acupoint injection of houttuynia cordata promotes corneal epithelial recovery,reduces the discomfort symptoms as well as increases tear secretion and the stability of tear film in dry eyes of convalescent herpes simplex keratitis.

关 键 词：单纯疱疹病毒性角膜炎 干眼症 穴位注射 鱼腥草 

分 类 号：R245.95[医药卫生—针灸推拿学]