宫腔灌注hCG对薄型子宫内膜IVF-ET结局的影响  

Effect of Intrauterine h CG Infusion on IVF-ET Outcome of Thin Endometrium

作　　者：王莉[1] WANG Li(Xuzhou Maternal and Child Health Hospital,Xuzhou 221000,China)

机构地区：[1]徐州市妇幼保健院,江苏徐州221000

出　　处：《中外医学研究》2020年第28期127-129,共3页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探讨宫腔灌注绒促性素(hCG)对薄型子宫内膜体外受精-胚胎移植(IVF-ET)结局的影响。方法:选择2018年4月-2019年7月于笔者所在医院就诊的薄型子宫内膜患者78例,根据治疗方式不同分为试验组(n=39)与对照组(n=39),两组均行IVF-E,试验组移植前予以宫腔灌注hCG,对照组未行宫腔灌注hCG,比较两组IVF-ET结局。结果:试验组治疗后的E2、LH、FSH水平显著高于对照组(P<0.05)。试验组治疗后的子宫内膜厚度、卵巢体积显著大于对照组(P<0.05)。试验组受精率、胚胎种植率、妊娠率显著高于对照组(P<0.05)。结论:移植前宫腔灌注hCG可改善薄型子宫内膜患者的子宫内膜容受性,改善IVF-ET结局,可推广于临床。Objective:To investigate the effect of intrauterine hCG infusion on IVF-ET outcome of thin endometrium.Method:A total of 78 patients with thin endometrium who were treated in our hospital from April 2018 to July 2019 were divided into experimental group (n=39) and control group (n=39) according to different treatment methods.IVF-ET was performed in both groups.hCG was infused into uterine cavity before transplantation in the experimental group,but not in the control group.Compared the IVF-ET outcome.Result:The levels of E2,LH and FSH in the experimental group were significantly higher than those in the control group (P<0.05).The endometrial thickness and ovarian volume of the experimental group were significantly larger than those of the control group (P<0.05).The fertilization rate,embryo implantation rate and pregnancy rate of the experimental group were significantly higher than those of the control group (P<0.05).Conclusion:hCG perfusion before transplantation can improve the endometrial receptivity and IVF-ET outcome of patients with thin endometrium,which can be widely used in clinic.

关 键 词：薄型子宫内膜 宫腔灌注 绒促性素 体外受精-胚胎移植 妊娠结局 

分 类 号：R714.8[医药卫生—妇产科学]