指长波动性不对称与精神分裂症的相关性  

Relationship between fluctuating asymmetry of digit length and schizophrenia

作　　者：陆宏[1,2] 王璐[3] 霍正浩[1,2] 赵君利[4] 党洁[1,2] 马占兵[1] LU Hong;WANG Lu;HUO Zheng-hao;ZHAO Jun-li;DANG Jie;MA Zhan-bing(Key Laboratory of Fertility Preservation and Maintenance of Ministry of Education/Basic Medical College,Yinchuan 750004,China;Key Laboratory of Reporoduction and Genetics in Ningxia,Yinchuan 750004,China;Reproductive Medical Center,Peking University People's Hospital,Beijing 100044,China;Reproductive Medical Center of General Hospital,Ningxia Medical University,Yinchuan 750004,China)

机构地区：[1]宁夏医科大学教育部生育力保持省部共建重点实验室/基础医学院,银川750004 [2]宁夏回族自治区生殖与遗传重点实验室,银川750004 [3]北京大学人民医院生殖医学中心,北京100044 [4]宁夏医科大学总院生殖医学中心,银川750004

出　　处：《解剖学报》2020年第5期792-795,共4页Acta Anatomica Sinica

基　　金：国家自然科学基金(31460272,30960154)。

摘　　要：目的探讨宁夏汉族女性指长波动性不对称(FA)与精神分裂症的关系。方法采用体质测量法,比较分析宁夏汉族女性292例(正常对照146例,精神分裂症患者146例)指长FA(2FA、3FA、4FA、5FA)及复合FA(CFA)的均值及其差异性。结果宁夏汉族女性正常对照组与精神分裂症患者组各指长FA均呈现2FA>4FA>3FA>5FA的趋势,患者组各FA均值均高于对照组,且2FA(P<0.01)、3FA、4FA(均P<0.05)差异显著;精神分裂症患者组2FA人数在FA≥0.04 mm组显著增高(P<0.01);精神分裂患者组各FA均值与发病年龄无相关性(P>0.05)。结论指长FA,尤其是2FA与宁夏汉族女性精神分裂症有关,可能为其早期筛查提供重要的预警信息。Objective To investigate the relationship between the fluctuating asymmetry(FA)of digit length and schizophrenia in females from Ningxia Han nationality.Methods The mean values and the differences of FA(2FA、3FA、4FA、5FA)and composite FA(CFA)of 292 individuals(controls:146;schizophrenia patients:146)were compared and analyzed by using anthropometry.Results The result showed the trend as 2FA>4FA>3FA>5FA in both schizophrenia patients and controls;The mean values of each FA were higher in patients than those of in controls.There were significant differences in 2FA(P<0.01),3FA,4FA(all P<0.05)between the two groups.In schizophrenia patients,the number in FA≥0.04 mm of 2FA was significantly higher(P<0.01);There were no relationship between FA and the age at presentation of schizophrenia(P>0.05).Conclusion FA of digit length,especially 2FA is correlated with schizophrenia in females from Ningxia Han nationality and may provide the important warning information for early diagnosis of the disease.

关 键 词：指长 波动性不对称 精神分裂症 体质测量法 女性 

分 类 号：Q983[生物学—人类学]