人工紫外线诱导皮肤参数变化的初步研究  

A Preliminary Study on Skin Characteristic Parameters after Solar-Simulated Radiation

作　　者：郑洪艳[1,2] 杨丽 朱建宇 雷芳敏 岳章 胡楠 贾雪婷 ZHENG Hongyan;YANG Li;ZHU Jianyu;LEI Fangmin;YUE Zhang;HU Nan;JIA Xueting(Chinese Academy of Inspection and Quarantine,Beijing 100176,China;Beijing Sino-German Union Cosmetic Institute Co.,Ltd.,Beijing 100123,China)

机构地区：[1]中国检验检疫科学研究院,北京100176 [2]北京中德联合化妆品研究所有限公司,北京100123

出　　处：《香料香精化妆品》2020年第5期53-55,85,共4页Flavour Fragrance Cosmetics

基　　金：中国检验检疫科学研究院基本科研业务专项(项目编号2018JK039);中国检验检疫科学研究院基本科研业务专项(项目编号2018JK040)。

摘　　要：借助Chromameter、Mexameter及Tewameter等仪器,对人工紫外线诱导后受试者皮肤颜色、皮肤血红素和黑色素含量以及皮肤水分流失量进行测试,探索经模拟日光照射后皮肤特性参数的变化趋势。结果表明,在多次低剂量照射过程中,皮肤L~*和ITA°值呈现降低趋势,a~*值、皮肤血红素及黑色素含量值逐渐升高,在停止紫外照射后的2周内,皮肤L~*和ITA°值逐渐升高,a~*值、皮肤血红素及黑色素含量值逐渐降低,但仍与对照组具有显著性差异;皮肤水分流失量在持续照射阶段及恢复阶段均未发生显著性改变。To explore the change of skin characteristic parameters after simulated sunlight exposure,the subject's skin color,content of skin hemoglobin and melanin,and transepidermal water loss(TEWL)after artificial UV induction were tested on 20 healthy Chinese females by using Chromameter,Mexameter and Tewameter.The results showed that during multiple low dose UV irradiation,L*values and ITA°value performed a decreasing trend,and the a*values,contents of skin hemoglobin and melanin increased gradually.Within 2 weeks after UV irradiation,L*values and ITA°increased,a*values and contents of skin hemoglobin and melanin decreased gradually,but all the obtained parameters showed significant different with that of control area.The TEWL value did not change significantly during the continuous irradiation phase and the recovery phase.

关 键 词：紫外线 最小红斑量 皮肤颜色 皮肤水分流失量 

分 类 号：R758.1[医药卫生—皮肤病学与性病学]