静脉用抗菌素对良性气管狭窄呼吸内镜介入治疗术后长期疗效的影响  

Effect of Intravenous Antibiotics on Long-term Curative Effect of Benign Tracheal Stricture after Respiratory Endoscopic Interventional Therapy

作　　者：赖朝丽 LAI Chao-li(Department of Respiratory and Critical Care Medicine,Liangping District People's Hospital,Chongqing,405200 China)

机构地区：[1]重庆市梁平区人民医院呼吸与危重医学科,重庆405200

出　　处：《世界复合医学》2020年第9期65-67,共3页World Journal of Complex Medicine

摘　　要：目的观察分析静脉用抗菌素对良性气管狭窄呼吸内镜介入治疗术后长期疗效。方法选取该院2017年2月—2019年2月收治的88例良性气管狭窄患者(均雾化吸入布地奈德悬液、阿米卡星),按照静脉用抗菌素时间治疗长短分为A组(44例,静脉用抗菌素时间≤14 d)和B组(44例,静脉用抗菌素时间≥30 d)。观察两组术后长期疗效、术后近期疗效、感染发生率以及治疗前后的气促评分等。结果两组治疗前临床指标比较差异无统计学意义(t=0.063、0.182、0.259、0.719,P>0.05),治疗后B组临床指标显著优于A组(t=5.054、8.552、2.785、7.278,P<0.05);A组术后近期疗效、感染发生率、术后长期疗效分别为100.00%、0.00%、45.45%,B组分别为100.00%、0.00%、93.18%,两组良性气管狭窄患者的术后近期疗效、感染发生率比较差异无统计学意义(χ2=0.000、0.000,P>0.05),B组良性气管狭窄患者的术后长期疗效显著高于A组(χ2=15.824,P<0.05)。结论静脉用抗菌素时间≥30 d相比起静脉用抗菌素时间≤14 d对良性气管狭窄呼吸内镜介入治疗术后长期疗效显著。Objective To observe and analyze the long-term effect of intravenous antibiotics on benign tracheal stricture after respiratory endoscopic interventional therapy.Methods A total of 88 patients with benign tracheal stenosis(both inhaled budesonide suspension and amikacin)were selected(from February 2017 to February 2019)in the hospital and were divided into group A according to the duration of intravenous antibiotic treatment(44 cases,intravenous antibiotic time less than or equal to 14 d)and group B(44 cases,intravenous antibiotic time greater than or equal to 30 d).Observe the long-term postoperative curative effect,short-term postoperative curative effect,infection incidence and shortness of breath scores before and after treatment in the two groups.Results The comparison of clinical indicators between the two groups before treatment was not statistically significant difference(t=0.063,0.182,0.259,0.719,P>0.05),and the clinical indicators of B group were significantly better than those of A group(t=5.054,8.552,2.785,7.278,P<0.05);the short-term curative effect,infection incidence,and long-term postoperative curative effect of group A were 100.00%,0.00%,and 45.45%,respectively,and group B were 100.00%,0.00%,and 93.18%,respectively.Two groups of patients with benign tracheal stenosis were operated on the short-term efficacy and the incidence of infection were not statistically significant difference(χ^2=0.000,0.000,P>0.05).The long-term efficacy of patients with benign tracheal stenosis in group B was significantly higher than that in group A(χ^2=15.824,P<0.05).Conclusion The long-term effect of intravenous antibiotics longer than or equal to 30 d is more significant for patients with benign tracheal stenosis after respiratory endoscopic interventional therapy.

关 键 词：静脉用抗菌素 良性气管狭窄 呼吸内镜 介入治疗 术后长期疗效 

分 类 号：R562.12[医药卫生—呼吸系统]