药学干预对合理使用抗菌药物的影响分析  

Analysis of the Influence of Pharmaceutical Intervention on Rational Use of Antibacterial Drugs

作　　者：张锐利[1] ZHANG Rui-li(Department of Pharmacy,Affiliated Hospital of Heze Medical College,Heze,Shandong Province,274000 China)

机构地区：[1]菏泽医学专科学校附属医院药学科,山东菏泽274000

出　　处：《中外医疗》2020年第27期19-21,共3页China & Foreign Medical Treatment

摘　　要：目的探析药学干预对合理使用抗菌药物产生的影响。方法随机选择2018年11月—2019年11月在该院使用抗菌药物治疗的100例呼吸系统疾病患者作为研究对象,并通过抽签法将研究对象等分为观察组及对照组。对照组采用常规抗菌药物用药指导,观察组在此基础上实施药学干预,对两组联合用药率、不合理用药率、病原学检测率、抗菌药物使用天数、抗菌药物治疗费用、住院时间以及患者满意度进行对比。结果观察组的联合用药率、不合理用药率、病原学检测率及总体满意率分别为16.00%、8.00%、56.00%、98.00%;对照组的联合用药率、不合理用药率、病原学检测率及总体满意率分别为32.00%、28.00%、38.00%、80.00%,两组差异有统计学意义(χ^2=12.176、14.037、12.934、12.682,P<0.05)。观察组的抗菌药物使用天数、抗菌药物治疗费用以及住院时间分别为(9.24±0.82)d、(3281.64±327.62)元、(10.02±0.93)d,对照组的抗菌药物使用天数、抗菌药物治疗费用以及住院时间分别为(11.63±1.09)d、(4193.29±410.92)元、(13.84±1.37)d。两组差异有统计学意义(t=5.382、6.087、5.931,P<0.05)。结论药学干预能够提升临床抗菌药物使用的合理性,使药物疗效得到提升,并且还能够节约药物资源,使患者的经济负担降低,保证患者对药物治疗更为满意。Objective To explore the influence of pharmaceutical intervention on the rational use of antibacterial drugs.Methods Convenient selection 100 patients with respiratory diseases who were treated with antibiotics in the hospital from November 2018 to November 2019 were selected as the research subjects,and the subjects were equally divided into observation group and control group by lottery.The control group was guided by conventional antimicrobial medication,and the observation group implemented pharmaceutical intervention on this basis.The combined medication rate,irrational medication rate,etiological detection rate,number of days of antimicrobial use,antimicrobial treatment costs,hospitalization time,and patients’satisfaction were compared.Results The combined drug use rate,irrational drug use rate,pathogen detection rate and overall satisfaction rate of the observation group were 16.00%,8.00%,56.00%,and 98.00%,respectively;the control group's combined drug use rate,irrational drug use rate,and pathogenic test overall satisfaction rate and overall satisfaction rate were 32.00%,28.00%,38.00%,80.00%,respectively.The difference was statistically significant between the two groups(χ^2=12.176,14.037,12.934,12.682,P<0.05).The number of days of antimicrobial use,the cost of antimicrobial treatment,and the length of stay in the observation group were(9.24±0.82)d,(3281.64±327.62)yuan,and(10.02±0.93)d,respectively.The number of days of antimicrobial use and the cost of antimicrobial treatment in the control group and the hospital stay was(11.63±1.09)d,(4193.29±410.92)yuan,and(13.84±1.37)d.The difference was statistically significant between the two groups(t=5.382,6.087,5.931,P<0.05).Conclusion Pharmacological intervention can improve the rationality of clinical antibacterial drug use,improve drug efficacy,save drug resources,reduce the economic burden of patients,and ensure that patients are more satisfied with drug treatment.

关 键 词：药学干预 抗菌药物 合理用药 满意度 

分 类 号：R969.3[医药卫生—药理学]