新生儿高胆红素血症病因分析及临床治疗效果评价  

Etiological Analysis of Neonatal Hyperbilirubinemia and Evaluation of Clinical Treatment Effect

作　　者：游森水[1] 曾靖平 YOU Sen-shui;ZENG Jing-ping(Department of Pediatrics,Xiamen Third Hospital,Xiamen,Fujian Province,361100 China)

机构地区：[1]厦门市第三医院儿科,福建厦门361100

出　　处：《中外医疗》2020年第27期37-39,共3页China & Foreign Medical Treatment

摘　　要：目的分析新生儿高胆红素血症病因分析及临床治疗效果。方法在该院患者中选方便取2019年3—9月247例高胆红素血症患儿作为该次研究对象,分析高胆红素血症患儿的病因并根据病因拟定提出相应的治疗方法。分析患儿患病的原因和患儿的治疗情况,比较新生儿高胆红素血症患儿治疗前后的血清总胆红素。结果247例患者中,患儿的病因有母体因素205例,占比83.00%,其中母体感染导致的75例,母体妊娠高血压疾病导致的55例,母体妊娠糖尿病导致的75例;患儿因素导致的40例,占比16.19%,其中新生儿感染导致患病的15例,新生儿ABO溶血导致的10例,新生儿头颅血肿导致的10例,新生儿g6pd缺乏导致的5例。未查明病因2例,占比0.81%。患儿治疗后显效175例,有效70例,无效2例,治疗有效率为99.19%。患儿治疗后的血清总胆红素(184.3±34.5)μmol/L低于治疗前(345.3±45.7)μmol/L,差异有统计学意义(t=44.180,P<0.05)。结论新生儿高胆红素血症的最主要病因是母体因素,因此要在患儿的围生期做好护理,包括对母体的妊娠期的高血压、糖尿病及母体感染给予相应的治疗。患儿的治疗有效率较高,患儿在治疗后血清总胆红素明显下降,临床治疗效果较佳。Objective To analyze the etiology and clinical treatment effects of neonatal hyperbilirubinemia.Methods A total of 247 children with hyperbilirubinemia from March to September 2019 were conveniently selected from the patients in the hospital as the study objects.The etiology of children with hyperbilirubinemia was analyzed and based on the etiology to propose corresponding treatment methods.Analyze the causes of the children's illness and the children's treatment,and compare the serum total bilirubin before and after the treatment of neonatal hyperbilirubinemia.Results Among the 247 patients,205 cases were caused by maternal factors,accounting for 83.00%.Among them,75 cases were caused by maternal infection,55 cases were caused by maternal hypertension in pregnancy,and 75 cases were caused by maternal gestational diabetes.Pediatric factors of 40 cases,accounting for 16.19%,including 15 cases of neonatal infections,10 cases of neonatal ABO hemolysis,10 cases of neonatal head hematoma,and 5 cases of neonatal g6pd deficiency.The cause was not identified in 2 cases,accounting for 0.81%.After treatment,175 cases were markedly effective,70 cases were effective,and 2 cases were ineffective.The effective rate of treatment was 99.19%.The serum total bilirubin(184.3±34.5)μmol/L of the child after treatment was lower than that before treatment(345.3±45.7)μmol/L,the difference was statistically significant(t=44.180,P<0.05).Conclusion The main cause of neonatal hyperbilirubinemia is maternal factors.Therefore,it is necessary to take care of the children during the perinatal period,including the maternal hypertension,diabetes and maternal pregnancy Infections should be treated accordingly.The effective rate of the treatment of children is higher.After treatment,the total serum bilirubin of the children decreases significantly,and the clinical treatment effect is better.

关 键 词：新生儿 高胆红素血症 病因分析 治疗效果 

分 类 号：R722[医药卫生—儿科]