血清C反应蛋白联合白细胞水平检测在小儿发热性疾病鉴别诊断中的应用  

Application of Serum C Reactive Protein Combined with Leukocyte Detection in the Differential Diagnosis of Febrile Diseases in Children

作　　者：冯一川 康雯 康平 Feng Yichuan;Kang Wen;Kang Ping(Department of Laboratory,Affiliated Children's Hospital of Zhengzhou University,Henan Children's Hospital,Zhengzhou Children's Hospital,Zhengzhou 450000;Zhengzhou No.2 People's Hospital,Zhengzhou 450000)

机构地区：[1]郑州大学附属儿童医院,河南省儿童医院,郑州儿童医院检验科,郑州450000 [2]郑州市第二人民医院,郑州450000

出　　处：《数理医药学杂志》2020年第11期1635-1636,共2页Journal of Mathematical Medicine

摘　　要：目的:探讨血清C反应蛋白联合白细胞水平检测在小儿发热性疾病鉴别诊断中的应用价值。方法:选取某院2016年1月~2019年1月收治的发热性疾病患儿90例,依据病原体检查结果分为细菌感染组(42例)和非细菌感染组(48例),测定两组血清C-反应蛋白(CRP)、白细胞计数(WBC)水平,比较两组患儿血清CRP、WBC水平,并分析CRP、WBC单独及联合诊断细菌感染组和非细菌感染组阳性检出率。结果:细菌感染组血清CRP、WBC水平均较非细菌感染组高,差异具有统计学意义(P<0.05);细菌感染组CRP、WBC及CRP+WBC阳性检出率均较非细菌感染组高,差异具有统计学意义(P<0.05)。结论:血清CRP、WBC联合检测在寻找小儿发热性疾病病因中发挥重要作用,为临床鉴别细菌感染和非细菌感染提供重要依据,为临床治疗疾病提供重要指导价值。Objective:To explore the value of serum C-reactive protein combined with leucocyte level detection in the differential diagnosis of febrile diseases in children.Methods:90 children with febrile diseases admitted to a hospital from January 2016 to January 2019 were selected and divided into bacterial infection group(42 cases)and non-bacterial infection group(48 cases)according to the results of pathogen examination.Serum levels of C-reactive protein(CRP)and white blood cell count(WBC)were measured.Serum levels of CRP and WBC were compared between the two groups.The positive detection rates of CRP and WBC detection alone and the combined detection in bacterial infection group and non-bacterial infection group were analyzed.Results:The serum levels of CRP and WBC in bacterial infection group were higher than those in non-bacterial infection group,and the difference was statistically significant(P<0.05).The positive detection rates of CRP,WBC and CRP+WBC in bacterial infection group were higher than those in non-bacterial infection group,and the difference was statistically significant(P<0.05).Conclusion:The combined detection of serum CRP and WBC plays an important role in searching for the etiology of febrile diseases in children.It provides an important basis for differentiating bacterial infection from non-bacterial infection and provides an important guiding value for clinical treatment of diseases.

关 键 词：小儿发热性疾病 血清C反应蛋白 白细胞 

分 类 号：R446.1[医药卫生—诊断学]