产后出血产妇应用麦角新碱治疗对其FIB、TT、PT、APTT的影响  

Effect of Ergometrine on FIB,TT,PT and APTT in Postpartum Hemorrhage

作　　者：黄慧 HUANG Hui(Ganzhou Municipal Hospital,Ganzhou 341000,China)

机构地区：[1]江西省赣州市立医院,江西赣州341000

出　　处：《中国医学创新》2020年第30期138-141,共4页Medical Innovation of China

摘　　要：目的:探讨产后出血产妇应用麦角新碱治疗对其FIB、TT、PT、APTT的影响。方法:选取2019年1-12月本院收治的产后出血产妇86例,按照随机数字表法将其分为对照组和研究组,各43例。对照组应用缩宫素治疗,研究组在对照组基础上联合麦角新碱治疗。比较两组产妇产后出血量、凝血指标以及不良反应发生情况。结果:治疗后,研究组SBP、DBP、血浆黏度及全血黏度均低于对照组,差异均有统计学意义(P<0.05)。研究组产后24 h内出血量均低于对照组,差异有统计学意义(P<0.05)。治疗后,研究组FIB水平低于对照组,TT、PT及APTT均长于对照组,差异均有统计学意义(P<0.05)。研究组不良反应发生总发生率为16.3%,与对照组的23.3%比较,差异无统计学意义(P>0.05)。结论:对于产后出血产妇采用缩宫素联合麦角新碱治疗,可有效调节产妇凝血指标,促凝效果更理想,降低产妇产后出血量,且治疗安全性高,可以在临床中进一步推广应用。Objective:To explore the effect of Ergometrine on FIB,TT,PT and APTT in postpartum hemorrhage.Method:Eighty-six patients with postpartum hemorrhage admitted to our hospital from January to December 2019 were selected.According to the number table method,they were randomly divided into control group and study group,43 cases in each group.The control group was treated with Oxytocin,the study group was treated with Ergometrine on the basis of the control group.Bleeding volume,coagulation indexes and adverse reactions were compared between the two groups.Result:After treatment,SBP,DBP,plasma viscosity and whole blood viscosity in the study group were all lower than those in the control group,with statistically significant differences(P<0.05).The blood loss in the study group within 24 h after delivery was lower than that in the control group,the difference was statistically significant(P<0.05).After treatment,FIB level of the study group was lower than that of the control group,TT,PT and APTT were all longer than that of the control group,and the difference was statistically significant(P<0.05).The total incidence of adverse reactions in the study group was 16.3%,there was no statistically significant compared with 23.3%in the control group(P>0.05).Conclusion:For patients with postpartum hemorrhage,Oxytocin combined with Ergometrine therapy can effectively regulate the coagulation indicators of patients,promote coagulation effect is more ideal,reduce the amount of postpartum hemorrhage,and the treatment safety is high,can be further promoted in clinical application.

关 键 词：麦角新碱 缩宫素 产后出血 出血量 凝血指标 

分 类 号：R714.461[医药卫生—妇产科学]