浓缩血小板治疗男女性功能障碍的现状与前景  

Analysis of the Present Situation and the Future Prospect of Enriched Platelet Treatment in Sexual Dysfunction of Men and Women

作　　者：魏世坤(综述) 程飚(审校) WEI Shi-kun;CHENG Biao(Department of Burn and Plastic Surgery,General Hospital of the Southern Theatre Command of the Chinese People's Liberation Army,Guangzhou 510010,Guangdong,China;Department of Plastic Repair Surgery,the Second People's Hospital of Panyu Guangzhou,Guangzhou 511430,Guangdong,China)

机构地区：[1]中国人民解放军南部战区总医院烧伤整形外科,广东广州510010 [2]广州市番禺区第二人民医院整形修复外科,广东广州511430

出　　处：《中国美容医学》2020年第10期23-29,共7页Chinese Journal of Aesthetic Medicine

基　　金：国家重点研发计划(编号:2017YFC1103301)。

摘　　要：目前性功能障碍的主要治疗方法为手术治疗、激素疗法和心理疗法等。每种疗法都有一定的不足,激素疗法有大量不良事件发生,对于激素水平正常或激素治疗禁忌证且无手术指征的患者只有心理疗法。浓缩血小板由许多生长因子及活性成分组成,在注射部位与周围细胞、细胞内基质和介体相互作用致组织再生,浓缩血小板的促血管生成及促组织再生作用可用于治疗男女性功能障碍。然而,目前支持浓缩血小板对于性功能改善的疗效科学证据还有待进一步积累。本文将以当前发表的文献为基础,将浓缩血小板治疗(Enriched platelet treatment,EPT)技术在治疗男女性功能障碍中的效果及可能性做科学的分析。期待今后有更多的循证医学证据出现。At present,the main treatment methods of sexual dysfunction are surgery,hormone therapy and psychotherapy.However,each therapy has its own disadvantages.There are a lot of adverse events in hormone therapy.For patients with normal hormone level or contraindications of hormone therapy and no indication for surgery,only psychotherapy is available.Enriched platelet is composed of many growth factors and active components.It interacts with surrounding cells,intracellular matrix and mediators at the injection site to cause tissue regeneration.The effects of enriched platelet on angiogenesis and tissue regeneration can be used to treat male and female sexual dysfunction.However,the scientific evidence supporting the therapeutic effect of enriched platelet on sexual function improvement needs to be further accumulated.Based on the current published literature,this paper will make a scientific analysis of the effect and possibility of enriched platelet treatment(EPT)in the treatment of male and female sexual dysfunction.It is expected that more evidence-based medical evidence will appear in the future.

关 键 词：浓缩血小板 富血小板血浆 女性性功能障碍 勃起功能障碍 佩罗尼病 

分 类 号：R711.77[医药卫生—妇产科学]