角膜含水量光学测量方法研究综述  

Review of Optical Measurement Methods for Corneal Water Content

作　　者：王森德 姚嘉丽 胡俊波 刘晓庆[1] 林列[1] 刘永基[1] 刘伟伟[1] Wang Sende;Yao Jiali;Hu Junbo;Liu Xiaoqing;Lin Lie;Liu Yongji;Liu Weiwei(Tianjin Key Laboratory of Microscale Optical Information Science and Technology,Institute of Modern Optics,Nankai University,Tianjin 300350,China)

机构地区：[1]南开大学现代光学研究所天津市微尺度光学信息技术科学重点实验室,天津300350

出　　处：《激光与光电子学进展》2020年第17期1-21,共21页Laser & Optoelectronics Progress

基　　金：国家重点研发计划(2018YFB0504400);天津市自然科学基金(19JCYBJC16800);强场激光物理国家重点实验室开放课题;中央高校基本科研业务费。

摘　　要：角膜含水量是反映眼睛健康水平的重要参数,在相关眼科疾病的诊断、屈光手术的参数设置和术前术后的诊治以及角膜有关的生物化学基础研究中都具有重要科学意义。主要介绍了基于光学测厚法、共焦拉曼谱、近红外吸收谱及太赫兹波谱成像等光学技术的角膜含水量测量方法原理及研究进展,并对各方法存在的优缺点作扼要的总结。Corneal water content is an important parameter that reflects the health level of the eyes.It is very crucial to the diagnosis of cornea-related ophthalmic diseases,the setting of parameters for a refractive surgery,the diagnosis and treatment before and after the surgery,and the basic research of biochemistry related to the cornea.This paper introduces the principles and research progresses of corneal water content measurement methods based on optical thickness measurement methods,confocal Raman spectroscopy,near-infrared absorption spectroscopy,and terahertz spectrum imaging.The advantages and disadvantages of these methods are also briefly summarized.

关 键 词：光谱学 角膜含水量 角膜厚度 红外吸收 太赫兹波成像 

分 类 号：O439[机械工程—光学工程]