双乙酰香味剂相关性闭塞性细支气管炎的研究进展  

Advances in flavoring-related bronchiolitis obliterans

作　　者：王苑颖 叶俏[1] Wang Yuanying;Ye Qiao(Department of Occupational Medicine and Toxicology,Clinical Center for Interstitial Lung Diseases,Beijing Chaoyang Hospital,Capital Medical University,Beijing 100020,China)

机构地区：[1]首都医科大学附属北京朝阳医院职业病与中毒医学科,间质性肺疾病临床诊疗与研究中心,北京100020

出　　处：《中华劳动卫生职业病杂志》2020年第9期717-720,共4页Chinese Journal of Industrial Hygiene and Occupational Diseases

基　　金：国家自然科学基金(81970061);首都临床特色应用研究(Z181100001718118)。

摘　　要：职业接触双乙酰香味剂可能导致作业人员闭塞性细支气管炎(BO)。自2002年双乙酰香味剂相关性BO病例报道以来,部分国家和地区的不同生产工业工人均有类似病例报道。目前国内尚未见相关病例报道。本文综述了双乙酰香味剂相关性BO的认识历程、职业接触机会、疾病临床表现以及可能发病机制的研究进展,以期提高对疾病的认识,推动预防工作的开展。Occupational exposure to the diacetyl flavoring may cause bronchiolitis obliterans(BO)in workers.The first case of flavoring-related bronchiolitis obliterans was reported in 2002.Since then,similar cases have been identified among workers in various production industries in some countries and regions.At present,there are no cases reported in China.In order to improve the awareness of the disease and promote the prevention work,this article reviews the research progress of case recognition,risk factors,clinical manifestation and possible pathogenesis.

关 键 词：细支气管炎 闭塞性 双乙酰香味剂 2 3-丁二酮 职业病 危险因素 

分 类 号：R562.21[医药卫生—呼吸系统]