弥散张量成像辅助复杂颅内肿瘤手术的研究进展  

Recent advance in diffusion tensor imaging in assisting surgery of complex intracranial neoplasms

作　　者：刘星吾 法志强[1] 何骁征[1] 张世忠[1] Liu Xingwu;Fa Zhiqiang;He Xiaozheng;Zhang Shizhong(Department of Neurosurgery,National Key Clinic Specialty,Neurosurgery Institute of Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration,Zhujiang Hospital,Southern Medical University,Guangzhou 510282,China)

机构地区：[1]国家临床重点专科,教育部工程技术研究中心,广东省脑功能修复与再生重点实验室,南方医科大学珠江医院神经外科,广州510282

出　　处：《中华神经医学杂志》2020年第10期1075-1079,共5页Chinese Journal of Neuromedicine

摘　　要：弥散张量成像(DTI)作为神经影像学研究的一种重要技术,能够反映颅内神经纤维束的结构变化,3D重建神经纤维束走行以及提供神经纤维束与颅内肿瘤之间的解剖毗邻信息。DTI的应用不仅可以指导临床医生优化手术路线,减少重要神经纤维束的损伤、提高肿瘤的全切率,同时还可以在一定程度上评估患者手术风险和术后疗效。笔者现按照颅内肿瘤所在的不同区域和累及的不同神经纤维束进行分类,逐一分析DTI对不同部位复杂颅内肿瘤手术的辅助作用,并对DTI应用的优势与不足进行总结,以期为今后复杂颅内肿瘤的手术提供参考依据。Diffusion tensor imaging(DTI)is a neuroimaging technique which provides exquisite details on tissue microstructure.DTI also plays an important role in 3D reconstruction and visualization of white matter tracts and providing information about the relationship between these tracts and the tumor mass.DTI can not only guide neurosurgeons to optimize the actual surgical procedures and avoid injures to intact,functioning tracts,but also can improve the total rate resection of tumor.At the same time,it can also assist in preoperative risk assessment and postoperative functional assessment.This review is classified by different tractographies involved in brain tumors;it summarizes the advantages and disadvantages of DTI in the last decade.Therefore,this review provides new research methods and evidence for the future complex intracranial tumor treatment.

关 键 词：颅内肿瘤 弥散张量成像 神经纤维束 

分 类 号：R445.2[医药卫生—影像医学与核医学] R739.41[医药卫生—诊断学]