55例新型冠状病毒肺炎患者临床特征  

Epidemiological and clinical characteristics of 55 patients with COVID-19

作　　者：董文逸[1] 黄高燕 谢周华[1] 林艳荣[1] 宋晓玲[1] 吴念宁[1] 韦善求 唐欷柯 DONG Wenyi;HUANG Gaoyan;XIE Zhouhua;LIN Yanrong;SONG Xiaoling;WU Nianning;WEI Shanqiu;TANG Xike(Guangxi AIDS Clinical Treatment Center,Nanning Fourth People′s Hospital,Nanning,Guangxi 530023,China)

机构地区：[1]南宁市第四人民医院,广西艾滋病临床治疗中心,广西南宁530023

出　　处：《中国热带医学》2020年第10期959-961,共3页China Tropical Medicine

基　　金：广西重点研发计划防控新型冠状病毒感染肺炎疫情应急科技攻关专项(No.桂科AB20059001)。

摘　　要：目的探讨新型冠状病毒肺炎(COVID-19)患者的临床和流行病学特征,为疫情的防控提供参考。方法以2020年1月23日—2月16日在某院确诊并收治的COVID-19患者55例为研究对象,收集患者近期是否到湖北出行,是否接触过来自湖北的人员,近期是否接触呼吸道疾病患者等流行病学资料,临床症状资料包括发热、乏力、干咳、肌肉疼痛、咳痰等,收集相关的实验室检测和影像学检查指标,分析COVID-19患者临床和流行病学特征。结果55例患者中男性27例,女性28例,平均年龄(43.11±17.91)岁。临床分型:轻型3例,普通型48例,重型3例,危重型1例,以普通型为主(87.27%)。家庭聚集性病例29例(52.73%),输入性病例19例(34.55%),近期接触到过湖北的人员27例(49.09%)。临床症状为干咳34例(61.82%),发热30例(54.55%),咳痰19例(34.55%),乏力18例(32.73%),无症状者6例(10.91%)。首次住院检测白细胞总数正常或降低者52例(94.55%),淋巴细胞计数减少12例(21.82%)。出现症状后5 d CT双肺毛玻璃样变46例(83.64%)。结论COVID-19患者以普通型为主,主要为输入性和家庭聚集性病例,同时也存在着无症状感染者。对COVID-19防控要严防输入性病例和人员的聚集,加强体温的监测。加强对确诊患者密切接触者的COVID-19核酸检测,及时发现无症状病例并进行隔离和治疗。Objective To explore the clinical and epidemiological characteristics of patients with coronavirus disease 2019,and we provide reference for the prevention and control of epidemic situation.Methods Fifty-five patients with COVID-19 diagnosed and admitted to the hospital were studied as the research object from January 23 to February 16,2020,we collected epidemiological data,such as whether patients had been a recent travel to Hubei,ever come into contact with people from Hubei,whether recent contact with patients with respiratory diseases;and clinical features include fever,fatigue,dry cough,muscle pain,cough,sputum,etc,collected related laboratory tests and imaging examination index,analyzed clinical and epidemiology features of COVID-19 patients.Results Among the 55 cases,27 were males and 28 were females,with an average age of(43.11±17.91)years.Among them,there were 3 cases of mild type,48 cases of normal type,3 cases of severe type and 1 case of critical type.The common type was dominant,accounting for 87.27%of the total cases.There were 29 cases of family cluster(52.73%).There were 19 imported cases(34.55%),and 27 recent contacts with persons from Hubei(49.09%).The clinical symptoms were dry cough in 34 cases(61.82%),fever in 30 cases(54.55%),sputum in 19 cases(34.55%),and fatigue in 18 cases(32.73%),and asymptomatic in 6 cases(10.91%).The total number of white blood cells was normal or decreased in 52 cases(94.55%),and the lymphocyte count was decreased in 12 cases(21.82%).There were 46 cases(83.64%)with ground-glass changes in both lungs on CT 5 days after the onset of symptoms.Conclusions COVID-19 patients were mainly normal type,mainly imported and family cluster cases,but there were also asymptomatic patients.The prevention and control of COVID-19 should strictly prevent imported cases and personnel gathering,and strengthen the monitoring of body temperature.Strengthen COVID-19 nucleic acid testing of confirmed close contacts,we couldtimely detect asymptomatic cases and conduct isolation and treatment.

关 键 词：新型冠状病毒肺炎 流行病学 输入性 

分 类 号：R195.4[医药卫生—卫生统计学] R511[医药卫生—卫生事业管理]