中国地鼠的剖宫产净化  

Caesarian Purification of Chinese Hamster

作　　者：张锐虎 王晨阳 王璐 余婧婧 王文桃 陈朝阳 ZHANG Ruihu;WANG Chenyang;WANG Lu;YU Jingjing;WANG Wentao;CHEN Zhaoyang(Laboratory Animal Center of Shanxi Medical University,Taiyuan 030001,China;Shanxi Key Laboratory of Experimental Animal Science and Animal Model of Human Disease,Taiyuan 030001,China)

机构地区：[1]山西医科大学实验动物中心,太原030001 [2]实验动物与人类疾病动物模型山西省重点实验室,太原030001

出　　处：《实验动物科学》2020年第4期1-4,9,共5页Laboratory Animal Science

基　　金：山西医科大学青年基金(No.201403)。

摘　　要：目的通过生物净化使中国地鼠的微生物、寄生虫质量控制级别达到清洁级标准。方法普通级中国地鼠剖宫产后获得的仔鼠由清洁级ICR小鼠代乳,记录仔鼠0~30日龄的体质量变化和存活情况,对离乳后的仔鼠进行微生物、寄生虫质量检测。结果本次实验对24窝普通级中国地鼠进行剖宫产手术,共获得新生仔鼠109只,其中5只死胎仔,最终代乳成活56只,代乳成功率为53.85%,离乳后的地鼠经随机检测均达到清洁级国家标准。结论本研究对中国地鼠进行了生物净化,进一步完善了中国地鼠的质量标准化,为中国地鼠的生产、应用提供了质量保障。Objective In order to make the quality control level of microbiology and parasitology of Chinese hamsters reach the clean standard through biological purification.Method First of all,the offspring of ordinary Chinese hamsters were delivered by cesarean section,and then the milk of clean grade ICR mice was substituted.At the same time,the changes of body weight and survival of 30-day-old offspring were recorded,and the microbiological and parasitological quality of weaned mice were tested.Result In this experiment,24 nests of ordinary Chinese hamsters were selected for cesarean section,and a total of 109 new born rats were obtained,of which 5 were dead,and 56 survived,with a success rate of 53.85%.After weaning,all the hamsters reached the clean national standard.Conclusion This study carried out biological purification of Chinese hamsters,further improved the quality standardization of Chinese hamsters,and provided quality guarantee for the production and application of Chinese hamsters.

关 键 词：中国地鼠 生物净化 剖宫产 

分 类 号：Q95[生物学—动物学]