PTX治疗尿毒症继发性甲状旁腺亢进的临床疗效观察  

Clinical efficacy of PTX in treatment of uremia with secondary hyperparathyroidism

作　　者：敖辉平 Ao Huiping(The People's Hospital of Xinyu City,Xinyu,Jiangxi 338000)

机构地区：[1]新余市人民医院,江西新余338000

出　　处：《基层医学论坛》2020年第31期4443-4444,共2页The Medical Forum

基　　金：新余市科技计划项目(20183090806)。

摘　　要：目的探讨甲状旁腺切除术(PTX)在尿毒症继发性甲状旁腺亢进(SHPT)中的临床效果。方法回顾性分析2017年12月—2019年12月于我院行PTX治疗的20例尿毒症SHPT患者的临床资料,比较术前及术后7 d、3个月及6个月时血钙、全段甲状旁腺激素(iPTH)及血磷水平、骨痛评分,并观察并发症情况。结果术后7 d、3个月、6个月血钙、iPTH及血磷水平均低于术前,差异有统计学意义(P<0.05);术后7 d、3个月、6个月骨痛评分低于术前,差异有统计学意义(P<0.05);20例SHPT患者均未出现并发症。结论PTX可提高尿毒症SHPT患者的治疗效果,降低血钙、iPTH及血磷水平,减轻骨痛,安全可靠,值得临床借鉴推广。Objective To investigate the effect of parathyroidectomy(PTX)on efficacy and safety in uremia patients with secondary hyperparathyroidism(SHPT).Methods The clinical data of 20 uremia patients with SHPT who were treated by PTX in the hospital from December 2017 to December 2019 were retrospectively analyzed.The serum calcium,intact parathyroid hormone(iPTH),serum phosphorus,ostealgia score were compared before surgery,after surgery for 7d,3 months and 6 months,and the complications were observed.Results The levels of serum calcium,iPTH,and serum phosphorus after surgery for 7d,3 months and 6 months were lower than those before surgery,with statistically significant difference(P<0.05);The ostealgia scores after surgery for 7d,3 months and 6 months were lower than those before surgery,with statistically significant difference(P<0.05);There were no complications in 20 patients with SHPT.Conclusion PTX in treatment of uremia patients with SHPT can improve curative effects,decrease the levels of serum calcium,iPTH and serum phosphorus,and alleviate the ostealgia,which is safe and reliable and worthy of extensive application.

关 键 词：尿毒症 继发性甲状旁腺亢进 甲状旁腺切除术 血钙 血磷 

分 类 号：R692.5[医药卫生—泌尿科学] R581.1[医药卫生—外科学]