生物型人工硬脑膜用于颅脑损伤硬膜修补术中的效果观察  

Effect of biological artificial dura mater in dural repair of craniocerebral injury

作　　者：曾多[1] 肖妮[1] 叶世阳[1] 胡稻[1] 胡斌[1] 刘传金 游涛[1] ZENG Duo;XIAO Ni;YE Shi-yang(Neurosurgery Department,Pingxiang People's Hospital,Pingxiang 337000,China)

机构地区：[1]萍乡市人民医院神经外科,337000

出　　处：《中国实用医药》2020年第29期1-3,共3页China Practical Medicine

摘　　要：目的探讨生物型人工硬脑膜用于颅脑损伤硬膜修补术中的效果。方法 60例拟行硬膜修补术治疗的颅脑损伤患者,按随机数字表法分为A组和B组,各30例。两组患者均行大骨瓣减压术治疗, A组行生物型人工硬脑膜修补, B组行自体膜修补,两组二期手术均为颅骨修补术。比较两组术后并发症发生情况、二期手术情况、预后格拉斯哥预后量表(GOS)分级。结果 A组术后并发症发生率10.00%低于B组的33.33%,差异有统计学意义(P<0.05)。两组二期手术硬膜外总引流量比较,差异无统计学意义(P>0.05);A组二期手术术中出血量(70.19±17.40)ml少于B组的(85.65±18.79)ml,手术时间(72.90±21.48)min短于B组的(92.65±24.05)min,差异有统计学意义(P<0.05)。两组患者预后GOS分级比较,差异无统计学意义(P>0.05)。结论颅脑损伤硬膜修补术中使用生物型人工硬脑膜修补能降低术后并发症发生率,为二期手术创造良好条件,缩短颅骨修补术用时,减少出血量,值得临床推广。Objective To discuss the effect of biological artificial dura mater in dural repair of craniocerebral injury. Methods A total of 60 patients with craniocerebral injury planned to undergo dural repair were divided into group A and group B according to random numerical table, with 30 cases in each group. Both groups were treated with large bone flap decompression, group A underwent bioartificial dura mater repair, group B underwent autologous membrane repair, and both groups were treated with skull repair. The occurrence of postoperative comlications, second-stage operation, Glasgow outcome scale(GOS) classification were compared between the two groups. Results The incidence of postoperative complications 10.00% of group A was lower than 33.33% of group B, and the difference was statistically significant(P<0.05). There was no statistically significant difference in total epidural drainage of the second stage operation between the two groups(P>0.05). The amount of intraoperative hemorrhage of second stage operation(70.19±17.40) ml of group A was less than(85.65±18.79) ml of group B, and operation time(72.90±21.48) min was shorter than(92.65±24.05) min of group B, and the difference was statistically significant(P<0.05). There was no statistically significant difference in GOS classification between the two groups(P>0.05). Conclusion Application of biological artificial dura mater in dural repair of craniocerebral injury can lower the incidence of postoperative complications, create good conditions for the second stage operation, shorten the time of cranial repair, and reduce the amount of hemorrhage. It is worthy of clinical promotion.

关 键 词：颅脑损伤 硬膜修补术 生物型人工硬脑膜 自体膜 预后 

分 类 号：R651.15[医药卫生—外科学]