456nm半导体蓝激光眩目效应研究  

Study on the dazzle effect of 456nm blue laser

作　　者：倪波 范应威 罗振坤 马琼 梁洁 康宏向 NI Bo;FAN Yingwei;LUO Zhenkun;MA Qiong;LIANG Jie;KANG Hongxiang(Graduate School, Anhui Medical University, Hefei 230032, China;Institute of Radiation Medicine, Academy of Military Medical Sciences, Academy of Military Science PLA China, Beijing 100850, China)

机构地区：[1]安徽医科大学研究生院,合肥230032 [2]中国人民解放军军事科学院军事医学研究院辐射医学研究所,北京100850

出　　处：《激光技术》2020年第6期738-741,共4页Laser Technology

摘　　要：为了探讨蓝激光眩目效应量效关系,利用视网膜电流图研究456nm半导体蓝激光照射兔眼的眩目效应,通过视网膜电流图b波振幅恢复时间评价蓝激光致眩效果,绘制剂量-恢复时间曲线,并通过眼底照相机观察激光辐照后的视网膜损伤情况。结果表明,456nm蓝激光眩目效果明显,视网膜电流图b波振幅的恢复时间随蓝激光辐照剂量的增加而延长,恢复时间与剂量间呈良好的线性关系,辐照后即刻和辐照24h后观察眼底未见损伤。本研究将为蓝激光的眩目应用提供了参考。In order to explore the dose effect relationship of blue laser dazzle effect,electroretinogram was used to evaluate the dazzle effect of a 456nm semiconductor blue laser on rabbit eyes.The dazzle effect of blue laser and its characteristics were evaluated by the recovery time of electroretinogram b-wave amplitude,the dazzling recovery time curves corresponding to different doses were drawn,and the damage of retina after laser irradiation was observed with fundus camera.The results show that the recovery time of b-wave amplitude of electroretinogram(ERG)is prolonged with the increase of laser irradiation dose,and there is a good linear relationship between the recovery time and the dose.No damage is found in the fundus immediately after irradiation and 24h later.This study will provide reference value for the application of blue laser dazzle.

关 键 词：医用光学 眩目效应 视网膜电流图 蓝激光 半导体激光器 

分 类 号：Q631[生物学—生物物理学]