小盘木中多样性二萜类化合物  

Diverse Diterpenoids from Microdesmis casearifolia

作　　者：韩光辉 任宇豪 范耀月 纪开龙 周彬 曹卫国[1] 岳建民 Han Guanghui;Ren Yuhao;Fan Yaoyue;Ji Kailong;Zhou Bin;Cao Weiguo;Yue Jianmin(Department of Chemistry,College of Science,Shanghai University,Shanghai 200444;State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203)

机构地区：[1]上海大学理学院化学系,上海200444 [2]中国科学院上海药物研究所新药研究国家重点实验室,上海201203

出　　处：《有机化学》2020年第9期2811-2816,共6页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(Nos.21532007,21772213);国家重大新药创制专项(No.2018ZX09711001-001-005);中国科学院战略生物资源计划(No.KFJ-BRP-008);中国科学院青年创新促进会资助项目。

摘　　要：从小盘木植物中分离鉴定了四个新二萜类化合物1~4,分别属于dolabrane烷型、玫瑰烷型、半日花烷型以及烟草烷型.综合利用各种光谱数据阐明了四个二萜类化合物的相对立体结构,并通过圆二色谱(ECD)数据确定了它们的绝对构型.Four new diterpenoids,casearoids A^D(1~4),including dolabrane,orosane,labdane,and cembrane,were isolated and characterized from Microdesmis casearifolia.Their structures were elucidated by extensive spectroscopic data analysis.The absolute configurations of these diterpenoids were established by analysis of the electronic circular dichroism(ECD)data.

关 键 词：小盘木 小盘木属 二萜化合物 小盘木素A^D 结构解析 圆二色谱(ECD)分析 

分 类 号：O629.61[理学—有机化学]