过敏原筛查在儿童分泌性中耳炎中的研究  

Allergen Screening in Children with Secretory Otitis Media

作　　者：赫莉 左路杰[1] 耿江桥[1] 王乐[2] 崔莉[1] 李国慧[3] 宋英鸾[1] HE Li;ZUO Lujie;GENG Jiangqiao;WANG Le;CUI Li;Li Guohui;SONG Yingluan(Department of Otolaryngology,Hebei Provincial Children’s Hospital,Shijiazhuang,Hebei 050000,China;Institute of Pediatrics,Hebei Provincial Children’s Hospital,Shijiazhuang,Hebei 050000,China;Clinical Laboratory,Hebei Provincial Children’s Hospital,Shijiazhuang,Hebei 050000,China)

机构地区：[1]河北省儿童医院耳鼻咽喉头颈外科,河北省石家庄050000 [2]河北省儿童医院儿研所,河北石家庄050000 [3]河北省儿童医院检验科,河北石家庄050000

出　　处：《中华耳科学杂志》2020年第5期833-837,共5页Chinese Journal of Otology

基　　金：京津冀基础研究合作专项暨河北省自然科学基金(H2018316006);河北省卫生健康委2020年度医学科学研究课题(20200662)。

摘　　要：目的分析过敏原筛查在儿童分泌性中耳炎中的结果并探讨其临床意义。方法选取住院治疗的100例慢性分泌性中耳炎患儿为SOM组,选取40例不伴分泌性中耳炎患儿为对照组,对血清过敏原筛查结果进行不同组间比较。结果总体过敏原阳性率、食入性过敏原阳性率、吸入性过敏原阳性率SOM组均高于对照组;食入性过敏原中牛奶、鸡蛋白、牛/羊肉组合SOM组均高于对照组;总体过敏原阳性项数、食入性过敏原阳性项数、吸入性过敏原阳性项数SOM组均高于对照组;以上差异均有统计学意义。SOM组中,总体过敏原阳性率随年龄增长呈下降趋势,总体过敏原阳性项数中位数随年龄增长逐渐下降,两者在四个年龄组间比较,差异均有统计学意义。结论过敏原刺激是分泌性中耳炎发生的病因之一,6岁以下患儿表现较为突出,其中食入性过敏原刺激作用不容小觑。Objective To study clinical significance of allergen screening in children with secretory otitis media.Methods Allergen screening data from 100 children with chronic secretory otitis media(SOM)and 40 children without secretory otitis media(controls)identified at our hospital were compared.Results Positive rates of allergens,including ingested and inhaled allergens,in the SOM group were higher than those in the control group.The rate of allergy to milk,chicken,beef and mutton in SOM group was higher than in the control group.The total number of positive allergens,the number of positive ingested allergens and the number of positive inhaled allergens were all higher in the SOM group than in the control group,although the overall rate of positive allergens and the median number of total positive allergens both decreased with age.There were statistical differences in all comparisons.Conclusion Allergic stimulation is one of the causes in secretory otitis media,especially in children less than 6 years old and for ingested allergens.

关 键 词：过敏原筛查 分泌性中耳炎 不同年龄组 食入性过敏原 

分 类 号：R764[医药卫生—耳鼻咽喉科]