全身麻醉药物在脓毒症围术期的抗炎作用  

Anti-inflammatory effects of general anesthetics in perioperative period of sepsis

作　　者：袁星星 李宏琴(综述) 曹丽君(审校)[1] YUAN Xingxing;LI Hongqin;CAO Lijun(Department of Anesthesiology,Second Xiangya Hospital,Central South University,Changsha 410011;Department of Anesthesiology,Peking University Shenzhen Hospital,Shenzhen Guangzhou 518000,China)

机构地区：[1]中南大学湘雅二医院麻醉科,长沙410011 [2]北京大学深圳医院麻醉科,广东深圳518000

出　　处：《临床与病理杂志》2020年第10期2764-2768,共5页Journal of Clinical and Pathological Research

摘　　要：脓毒症与机体多系统、多器官病理生理密切相关,其可致机体免疫功能紊乱,影响内环境的稳定性。脓毒症患者的麻醉风险极高。大量研究显示全身麻醉药物具有免疫调节作用,其中潜在的抗炎作用有助于减轻脓毒症引发的全身炎症反应,对脓毒症患者预后具有积极意义。因此,深入研究全身麻醉药物的抗炎作用对脓毒症患者围术期用药具有重要指导意义。Sepsis is closely related to the multi-system and multi-organ pathophysiology of the body,which can cause immune dysfunction and affect the stability of the internal environment.In such patients,the risk of surgery and anesthesia is extremely high.A large number of studies have shown that general anesthetics have immunomodulatory effects,and potential anti-inflammatory effects help to alleviate the systemic inflammatory response caused by sepsis,which has positive significance for the prognosis of patients with sepsis.Therefore,in-depth study of antiinflammatory effects of anesthetics has important guiding significance for perioperative medication in patients with sepsis.

关 键 词：全身麻醉药物 围术期 脓毒症 抗炎 

分 类 号：R614.2[医药卫生—麻醉学]