超声引导下囊内消融与刺穿囊壁消融治疗甲状腺良性囊实性结节的对比研究  

Ultrasound-Guided Intracapsular Thermal Ablation and Puncture Cystic Wall Thermal Ablation in the Treatment of Benign Solid-Cystic Thyroid Nodules:A Comparative Study

作　　者：韦文姜[1] 田作富 李立恒[1] 唐迎红[1] 徐谷根[2] 肖承江[1] WEI Wenjiang;TIAN Zuofu;LI Liheng;TANG Yinghong;XU Gugen;XIAO Chengjiang(Department of Intervention,Guangdong Second Provincial General Hospital,Guangzhou 510317,China;不详)

机构地区：[1]广东省第二人民医院介入科,广东广州510317 [2]广东省第二人民医院内分泌科,广东广州510317

出　　处：《中国医学影像学杂志》2020年第10期770-773,共4页Chinese Journal of Medical Imaging

摘　　要：目的对比囊内消融与刺穿囊壁消融治疗甲状腺良性囊实性结节的安全性与有效性,探索甲状腺良性囊实性结节的消融方法。资料与方法纳入细针穿刺活检证实为良性的98枚甲状腺囊实性结节,按囊壁消融方式分为囊内消融组与刺穿囊壁消融组,比较两组间术前和术后即刻、1、6、12个月的甲状腺结节体积。结果囊内消融组与刺穿囊壁消融组术后即刻结节体积均显著缩小[(57.32±8.56)%、(55.92±7.87)%],两组术后即刻与术后1个月结节缩小率差异无统计学意义(P=0.216、P=0.087)。刺穿囊壁消融组术后6个月与12个月结节体积缩小率大于囊内消融组,差异有统计学意义(P=0.026、P<0.001)。刺穿囊壁消融组与囊内消融组的并发症发生率差异无统计学意义(P>0.05)。结论囊内消融与刺穿囊壁消融治疗甲状腺良性囊实性结节均安全有效,刺穿囊壁消融更有利于结节消融后吸收缩小。Purpose To compare the safety and effectiveness of intracapsular thermal ablation and puncture cystic wall thermal ablation in the treatment of benign solid-cystic thyroid nodules,and to explore a better ablation method for benign solid-cystic thyroid nodules.Materials and Methods Ninety-eight benign solid-cystic thyroid nodules confirmed by fine needle aspiration biopsy were included,and then divided into the intracapsular ablation group and the puncture cystic wall ablation group according to the ablation method of cystic wall.The thyroid nodule volumes were recorded before,immediately,at 1,6 and 12 months after operation.Results The volume of nodule immediately after the operation in the intracapsular ablation group and the puncture wall ablation group was significantly reduced[(57.32±8.56)%,(55.92±7.87)%].There was no statistically significant difference in the reduction rate of the nodules immediately after operation and 1 month after operation in the two groups(P=0.216,P=0.087).The rate of nodule volume reduction at 6 months and 12 months after puncturing the cyst wall ablation group was greater than that in the intracapsular ablation group,with significant difference(P=0.026,P<0.001).There was no statistically significant difference in the incidence of complications between intracapsular ablation group and the puncture cystic wall ablation group(P>0.05).Conclusion Both intracapsular ablation and puncture cyst wall ablation are safe and effective for the treatment of benign cystic and solid thyroid nodules.Puncture cyst wall ablation is more conducive to the absorption and reduction of nodules after ablation.

关 键 词：甲状腺结节 消融技术 超声检查 介入性 超声检查 穿刺抽液术 活组织检查 针吸 治疗结果 

分 类 号：R445.1[医药卫生—影像医学与核医学] R581[医药卫生—诊断学]