电压调制型高灵敏电化学发光分析  

Voltage Modulated Electrochemiluminescence for Highly Sensitive Detection

作　　者：张晶晶[1,2] 金融 方丹君 江德臣 ZHANG Jingjing;JIN Rong;FANG Danjun;JIANG Dechen(School of Pharmacy,Nanjing Medical University,Nanjing 211166,China;State Key Laboratory of Analytical Chemistry for Life Science,School of Chemistry and Chemical Engineering,Nanjing University,Nanjing 210023,China)

机构地区：[1]南京医科大学药学院,南京211166 [2]南京大学化学化工学院,生命分析化学国家重点实验室,南京210023

出　　处：《高等学校化学学报》2020年第11期2421-2425,共5页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金(批准号:21974071)资助.

摘　　要：报道了一种电压调制型电化学发光分析技术,通过在施加恒定电压的基础上叠加一个小脉冲电压,可将鲁米诺-过氧化氢体系的电化学发光强度提升近2倍.电化学发光强度与过氧化氢浓度在1.0 nmol/L^200μmol/L范围内呈现良好的线性关系,检出限低至0.24 nmol/L(S/N=3).研究结果表明,通过电压调制模式可有效提高电化学发光强度,为深入理解电极界面电化学过程提供了新技术和数据.A voltage modulated electrochemiluminescent(ECL)method is established for highly sensitive detection.In this new strategy,a small voltage is imposed at a constant voltage that could increase ECL intensity from luminol-hydrogen peroxide by ca.2 times.This ECL intensity shows a good linear relationship with the concentration of hydrogen peroxide in the range of 1 nmol/L-200μmol/L with a detection limit of 0.1 nmol/L(S/N=3).The results exhibit that the voltage modulated ECL could be an effective way to increase ECL intensity,and more importantly,used to study the electrochemical process at the electrode interface.

关 键 词：电化学发光 电压调制 鲁米诺 过氧化氢 高灵敏检测 

分 类 号：O657[理学—分析化学]