萍乡市妊娠早期妇女碘营养状况及其与甲状腺功能的关系  

Iodine Nutritional Status of Early Pregnancy Women and Its Relationshipwith Thyroid Function in Pingxiang City

作　　者：高海波[1] 钟丽[1] 黄永建[1] 肖冬梅[1] 张雅薇[1] 谢勇丽[1] 龚玉萍[1] 赖轻舟 杨洲[1] 苏晓清[1] GAO Hai-bo;ZHONG Li;HUANG Yong-jian;XIAO Dong-mei;ZHANG Ya-wei;XIE Yong-li;GONG Yu-ping;LAI Qing-zhou;YANG Zhou;SU Xiao-qing(Department of Endocrinology,Pingxiang People's Hospital,Pingxiang 337000,Jiangxi,China)

机构地区：[1]萍乡市人民医院内分泌科,江西萍乡337000

出　　处：《医学信息》2020年第21期76-78,共3页Journal of Medical Information

基　　金：江西省卫生计生委科技计划项目(编号:20187200)。

摘　　要：目的调查萍乡市妊娠早期妇女碘营养及甲状腺功能状况,并探讨碘营养状况与甲状腺功能的关系,为萍乡地区妇女妊娠期间科学补碘提供参考。方法选取2018年1月~2019年12月萍乡市妊娠早期妇女318例,检测其尿碘、游离三碘原氨酸(FT3)、游离甲状腺激素(FT4)、促甲状腺受体激素(TSH)、促甲状腺受体抗体(TR-Ab)及抗甲状腺过氧化物酶抗体(TPO-Ab)的水平,分析该地区妊娠早期妇女碘营养水平及其与甲状腺功能之间的关系。结果318例妊娠早期妇女尿碘中位数为260.98μg/L,为轻度碘超适量;另外,碘缺乏、碘适量、碘超适量、碘过量妇女分别占21.38%、39.62%、31.76%、7.23%。妊娠早期碘缺乏与碘适量妇女甲状腺功能异常率比较,差异无统计学意义(P>0.05);碘适量与碘超适量及碘过量妇女甲状腺功能异常的患病率比较,差异无统计学意义(P>0.05);碘适量与碘异常妇女甲状腺功能异常率比较,差异有统计学意义(P<0.05)。结论萍乡市妊娠早期妇女总体碘充足,仅部分存在轻度碘超适量,中重度碘缺乏或碘过量较少。另外,碘异常较碘适宜更易出现甲状腺功能异常,妊娠早期妇女应检测尿碘水平以指导科学补碘。Objective To investigate the status of iodine nutrition and thyroid function in early pregnancy women in Pingxiang City,and to explore the relationship between iodine nutrition status and thyroid function,so as to provide references for scientific iodine supplementation during pregnancy in Pingxiang area.Methods A total of 318 early pregnancy women in Pingxiang City from January 2018 to December 2019 were selected,and their urine iodine,free triiodonine(FT3),free thyroid hormone(FT4),thyroid stimulating receptor hormone(TSH),the level of thyroid stimulating receptor antibody(TR-Ab)and anti-thyroid peroxidase antibody(TPO-Ab)was analyzed to analyze the iodine nutrition level of women in early pregnancy in the region and its relationship with thyroid function.Results The median urinary iodine of 318 women in early pregnancy was 260.98μg/L,which was a moderate amount of iodine;in addition,women with iodine deficiency,moderate iodine,excessive iodine,and iodine excess accounted for 21.38%,39.62%,31.76%,and 7.23%,respectively.There was no statistically significant difference in the thyroid dysfunction rate of women with iodine deficiency and adequate iodine in early pregnancy(P>0.05);There was no significant difference in the prevalence of thyroid dysfunction in women with moderate iodine and super-moderate iodine and iodine overdose(P>0.05);the difference between moderate iodine and iodine abnormal thyroid dysfunction rate in women was statistically significant(P<0.05).Conclusion The women in Pingxiang City had sufficient iodine in the first trimester.Only some of them had mild iodine excess,and moderate to severe iodine deficiency or iodine excess are less.In addition,abnormal iodine was more prone to abnormal thyroid function than suitable iodine.Women in early pregnancy should test urine iodine level to guide scientific iodine supplementation.

关 键 词：妊娠早期 碘营养 甲状腺功能 

分 类 号：R581[医药卫生—内分泌]