E-4,5-二苯基-2-吡咯烷酮的高立体选择性合成  

Highly Stereoselective Synthesis of E-4, 5-Disubstituted-2-Pyrrorlidinones

作　　者：郑可利[1] 

机构地区：[1]三明高等专科学校化学与生物工程系,福建三明365004

出　　处：《洛阳师范学院学报》2002年第5期44-46,共3页Journal of Luoyang Normal University

摘　　要：采用PTC法高立体选择性合成了E 4.5 二苯基 2 吡咯烷酮 ,反式异构体与顺式异构体之比为 97∶3,产率高达 74% ,其结构用1HNMR和MS表征 .E 4,5 Disubstituted 2 Pyrrolichinones was highly stereoselective synthesized under phase transfer catalysis, trans:cis was 97:3; the yield of the product was 74%; structures of product was confirmed by HNMR and MS.

关 键 词：E-4 5-二苯基-2-吡咯烷酮 高立体选择性合成 PTC法 药物中间体 结构表征 钙拮抗剂 

分 类 号：TQ463.53[化学工程—制药化工]