三宝木属植物化学成分及其药理活性研究进展  

Study progress on chemical constituents and biological activities of Trigonostemon genus

作　　者：王博闻 郁萌 冯剑[2] 刘洋洋[2] 陈德力[2,3] 刘平怀[1] WANG Bo-wen;YU Meng;FENG Jian;LIU Yang-yang;CHEN De-li;LIU Ping-huai(School of Chemical Engineering and Technology,Hainan University,Haikou 570228,China;Hainan Provincial Key Laboratory of Resources Conservation and Development of Southern Medicine,Hainan Branch Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences&Peking Union Medical College,Haikou 570311,China;Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100193,China)

机构地区：[1]海南大学化学工程与技术学院,海南海口570228 [2]中国医学科学院北京协和医学院药用植物研究所海南分所海南省南药资源保护与开发重点实验室,海南海口570311 [3]中国医学科学院北京协和医学院药用植物研究所,北京100193

出　　处：《中国中药杂志》2020年第19期4589-4597,共9页China Journal of Chinese Materia Medica

基　　金：海南省自然科学基金面上项目(219MS101)。

摘　　要：三宝木属Trigonostemon sp.植物隶属于大戟科Euphorbiaceae,全世界约有50种,分布于亚洲的热带和亚热带地区,我国有10种,主产于海南、云南以及广西等南部省区。植物化学研究发现其主要成分为萜类和生物碱类等;现代药理研究表明其具有细胞毒、抗病毒、抗菌以及抗炎等多种药理活性。该文综述了近十年国内外三宝木属植物的化学成分及药理活性研究进展,以期为该属植物的进一步研究与开发利用提供科学依据和参考。The plants of the Trigonostemon sp.genus(Euphorbiaceae family)comprising about 50 species worldwide are mainly distributed in tropical and subtropical Asia,10 species of which can be found in southern of China.Phytochemical studies on the plants in the genus have demonstrated a large amount of terpenoids and alkaloids.Modern pharmacological studies have demonstrated cytotoxicity,antivirus,antibacterial,anti-inflammation and other pharmacological activities.In this paper,chemical compositions and biological activities of Trigonostemon genus at home and abroad over the past decade were summarized,in order to provide scientific basis for the further development and utilization of Trigonostemon plants.

关 键 词：三宝木属 二萜 生物碱 药理活性 

分 类 号：R284.1[医药卫生—中药学] R285[医药卫生—中医学]