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作 者:孟改利 杨佩华 成晓悦 康茹 赵侃侃 于壮 谢云 MENG Gaili;YANG Peihua;CHENG Xiaoyue;KANG Ru;ZHAO Kankan;YU Zhuang;XIE Yun(Medical Laboratory Center,Northwest Women′s and Children′s Hospital,Xi′an,Shaanxi 710061,China)
机构地区:[1]西北妇女儿童医院医学检验中心,陕西西安710061
出 处:《检验医学与临床》2020年第21期3130-3132,共3页Laboratory Medicine and Clinic
摘 要:目的对孕期乙型肝炎五项、梅毒、艾滋病免费检测的结果进行分析,为做好优生优育工作提供科学依据。方法对西北妇女儿童医院2016年1月至2019年12月门诊首次孕检,且同意接受乙型肝炎五项、梅毒、艾滋病免费检测的50609例孕妇的检测结果进行统计分析。结果孕妇HBsAg阳性率为2.85%,HBsAb阳性率为63.04%,乙型肝炎五项全阴性率为34.01%。HBsAg阳性率逐年降低(χ2=7.932,P=0.047),HBsAb阳性率也逐年降低(χ2=4.046,P<0.001),乙型肝炎五项全阴性率却逐年升高(χ2=4.558,P<0.001),差异均有统计学意义。孕妇梅毒螺旋体(TP)抗体阳性率为0.25%;人类免疫缺陷病毒(HIV)抗体阳性率为0.08‰。TP抗体阳性率与HIV抗体阳性率虽有逐年上升的趋势,但差异无统计学意义(χ2=5.536,P=0.136;χ2=2.052,P=0.515)。结论西安市妊娠合并乙型肝炎阳性率逐年降低但仍较高,且妊娠合并梅毒、艾滋病阳性率仍维持在较高的水平。在孕期尤其是孕前和孕早期大力推行乙型肝炎五项、梅毒、艾滋病免费检测,提高孕检率,对提高优生优育率具有十分重要的意义。Objective To analyze the results of free testing of five items of hepatitis B,syphilis and AIDS during pregnancy,so as to provide scientific basis for eugenics.Methods The results of 50609 pregnant women who accepted free five items of hepatitis B,syphilis and AIDS tests from January 2016 to December 2019 in the hospital were statistically analyzed.Results The positive rate of HBsAg was 2.85%,the positive rate of HBsAb was 63.04%,and the total negative rate of five items of hepatitis B was 34.01%.The positive rate of HBsAg decreased year by year(χ2=7.932,P=0.047),the positive rate of HBsAb was also decreased year by year(χ2=4.046,P<0.001),but the total negative rate of five items of hepatitis B increased year by year(χ2=4.558,P<0.001).The positive rate of TP antibody in pregnant women was 0.25%and that of HIV antibody was 0.08‰.Although the positive rate of TP antibody and the positive rate of HIV antibody increased year by year,but the difference was not statistically significant(χ2=5.536,P=0.136;χ2=2.052,P=0.515).Conclusion In Xi′an City,the positive rate of pregnancy complicated with hepatitis B is decreasing year by year,but it is still high,and pregnancy complicated with syphilis and AIDS is still at a high level.It is of great significance to vigorously promote the free detection of five items of hepatitis B,syphilis and AIDS during pregnancy,especially before and in the early pregnancy,so as to improve the pregnancy examination rate and improve the eugenics rate.
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