补体系统在荨麻疹性血管炎诊疗及预后中的价值  

The values of complement system in the diagnosis,treatment and prognosis of urticarial vasculitis

作　　者：刘海波[1] 桑红[1] Liu Haibo;Sang Hong(Department of Dermatology,General Hospital of Eastern Theater Command,Nanjing 210002,China)

机构地区：[1]东部战区总医院(原南京军区南京总医院)皮肤科,南京210002

出　　处：《中华检验医学杂志》2020年第9期874-877,共4页Chinese Journal of Laboratory Medicine

基　　金：江苏省皮肤病学创新团队项目 (CXTDA2017038)。

摘　　要：荨麻疹性血管炎(UV)是一种免疫复合物介导的Ⅲ型超敏反应,其病理上表现为白细胞碎裂性血管炎,而补体激活在UV发病中发挥关键作用。血清补体水平检测是对UV进行诊断分型的基础,其对提示病情轻重及判断疗效和预后有重要意义。应当重视补体成分检测在UV诊疗及预后中的价值。Urticarial vasculitis(UV)is a typeⅢhypersensitivity reaction mediated by immune complexes,and it demonstrates leukocytoclastic vasculitis pathologically.Complement activation plays a crucial role in UV development.Serum complement level can not only be helpful for UV classification but also be of great value in predicting illness severity,treatment response and prognosis.Therefore,attention should be paid to complement measurement in the diagnosis and treatment of UV.

关 键 词：荨麻疹 血管炎 补体激活 补体C1Q 自身抗体 预后 

分 类 号：R758.24[医药卫生—皮肤病学与性病学] R446.6[医药卫生—临床医学]