皮内针调理肝肺法治疗慢性难治性咳嗽的临床效果  

Clinical effect of treating chronic refractory cough with intradermal needle regulating liver and lung

作　　者：刘志国[1,2] 李海霞 王蕾[1] 边永君[1] 李光熙[1] 李国勤[1] 荣毅[1] 亢秀红 LIU Zhiguo;LI Haixia;WANG Lei;BIAN Yongjun;LI Guangxi;LI Guoqin;RONG Yi;KANG Xiuhong(Department of Respiratory,Guang′anmen Hospital,China Academy of Chinese Medical Sciences,Beijing100053,China;Training Center,Guang′anmen Hospital,China Academy of Chinese Medical Sciences,Beijing100053,China;Department of Dermatology,Chongqing Traditional Chinese Medicine Hospital,Chongqing402760,China;Department of Gastroenterology,Beijing Hospital of Traditional Chinese Medicine,Capital Medical University,Beijing100010,China)

机构地区：[1]中国中医科学院广安门医院呼吸科,北京100053 [2]中国中医科学院广安门医院实训中心,北京100053 [3]重庆市中医院皮肤美容科,重庆402760 [4]首都医科大学附属北京中医医院消化科,北京100010

出　　处：《中国医药导报》2020年第30期173-177,共5页China Medical Herald

基　　金：中国中医科学院广安门医院国家中医临床研究示范基地科研专项暨所级科研基金课题(2014S282)。

摘　　要：目的研究皮内针调理肝肺法治疗慢性难治性咳嗽的临床效果。方法根据Excel生成随机数字表,采用随机、对照、单盲的方法将2015年6月—2016年3月中国中医科学院广安门医院门诊诊断为肝火犯肺型慢性难治性咳嗽24例患者分为治疗组和对照组,每组各12例。两组均予以基础治疗,在此基础上,治疗组给予皮内针治疗,对照组给予真穴安慰针治疗。治疗4周及治疗结束4周随访1次。以咳嗽症状积分、莱切斯特咳嗽量表(LCQ)和咳嗽视觉模拟评分(VAS)得分作为主要评估指标。结果研究过程中对照组脱落3例,失访2例,出差1例,剩余9例。咳嗽症状积分:日间咳嗽时间点比较差异、交互作用差异均有统计学意义(均P<0.05),组间比较差异无统计学意义(P>0.05)。夜间咳嗽评分时间点比较差异有统计学意义(均P<0.05),组间比较及交互作用差异均无统计学意义(均P>0.05)。组内比较:治疗4周后、疗程结束后4周,治疗组日间咳嗽积分和夜间咳嗽积分均较治疗前降低,对照组夜间咳嗽积分较治疗前降低(均P<0.05)。VAS评分:咳嗽程度、咳嗽频率评分组间比较、时间点比较差异均有统计学意义(均P<0.05),交互作用差异无统计学意义(P>0.05)。夜间咳嗽评分时间点比较差异有统计学意义(均P<0.05),组间比较及交互作用差异均无统计学意义(均P>0.05)。组内比较:治疗4周后、疗程结束后4周,两组的咳嗽程度、咳嗽频率和夜间咳嗽评分均较治疗前降低(均P<0.05)。组间比较:治疗4周后、疗程结束后4周,治疗组的咳嗽程度、咳嗽频率评分均低于对照组(均P<0.05)。LCQ评分:生理部分、心理部分、社会部分评分时间点比较差异有统计学意义(均P<0.05),组间比较及交互作用差异均无统计学意义(均P>0.05)。总分的组间比较、时间点比较、交互作用差异均无统计学意义(均P>0.05)。组内比较:治疗4周后、疗程结束后4周,治疗组生理�Objective To study the clinical effect of treating chronic refractory cough with intradermal needle regulating liver and lung.Methods According to Excel,a random number table was generated,and the 24 patients diagnosed as liver fire invading lung type chronic refractory cough in the outpatient clinic of Guang′anmen Hospital,China Academy of Chinese Medical Sciences from June 2015 to March 2016 were divided into treatment group and control group by random,controlled and single blind method,with 12 cases in each group.Both groups were given basic treatment,on this basis,the treatment group was given intradermal needle treatment,and the control group was given true acupoint comfort needle treatment.Treatment was performed for four weeks,and one follow-up was performed after four weeks of treatment.Cough symptom score,Leicester cough questionnaire(LCQ)and cough visual analogue scale(VAS)scores were used as the main evaluation indicators.Results During the study,three cases of abscission,two cases of loss of follow-up,one case of business trip and the remaining nine cases were in the control group.Cough symptom scores:there were statistically significant differences in the time points and the interaction of daytime cough between the two groups(all P<0.05),but no statistically significant differences between the two groups(P>0.05).The differences of night cough score at time points were statistically significant(all P<0.05),while the differences between the two groups and interaction were not statistically significant(all P>0.05).Intra-group comparison:after four weeks of treatment and four weeks after the end of the treatment course,the scores of daytime cough and night cough in the treatment group were all lower than those before treatment,and the scores of night cough in the control group were lower than those before treatment(all P<0.05).VAS score:there were statistically significant differences in the scores of cough degree and cough frequency between groups and at time points(all P<0.05),but no statistically si

关 键 词：皮内针 难治性咳嗽 咳嗽视觉模拟量表 莱切斯特咳嗽量表 咳嗽症状积分 

分 类 号：R265.11[医药卫生—中医外科学]