我院注射用帕瑞昔布钠药物利用评价标准的建立与应用  

Establishment and Application of DUE Standard for Parexib Sodium for Injection in Our Hospital

作　　者：王芳[1] 李小东[1] 任心慈[1] 桑翩翩 许静语 钱文 Wang Fang;Li Xiaodong;Ren Xinci;Sang Pianpian;Xu Jingyu;Qian Wen(Department of Pharmacy,People’s Hospital of Huaibei City,Anhui Huaibei 235000,China)

机构地区：[1]淮北市人民医院药剂科,安徽淮北235000

出　　处：《中国药师》2020年第10期1974-1977,共4页China Pharmacist

摘　　要：目的:建立注射用帕瑞昔布钠药物利用评价(DUE)标准,评价其临床使用的合理性和规范性,为临床合理用药提供参考。方法:参考药品说明书、相关指南和专家共识建立注射用帕瑞昔布钠DUE标准。设计患者使用调查表,依据制定的DUE标准评价我院2019年1~10月帕瑞昔布钠使用的合理性与规范性。结果:用药指征符合标准率为90.0%;用药过程中各项标准符合率为65.0%~100.0%,存在超剂量用药、用药过程中未按照要求监测血压、联合用药不合理、配伍禁忌等方面的不合理现象;用药结果符合标准率90.0%。结论:建立药物DUE标准,可促进药物评价工作的标准化和规范化;发现临床用药中的问题,有利于提高临床合理用药水平。Objective:To establish the drug use evaluation(DUE)standard for parexib sodium for injection to evaluate the rationality and standardization of clinical use,so as to provide references for rational clinical use.Methods:The DUE standard for parecoxib sodium for injection was established by referring to the drug manuals,related guidelines and expert consensus,and the questionnaire of the use of parecoxib sodium for injection was designed.The electronic medical records of the use of parecoxib sodium for injection from January to October in 2019 were consulted to evaluate the drug use according to the developed DUE standard.Results:The compliance rate of drug indication was 90.0%.The compliance rate of various standards in the process of drug use was 65.0%-100.0%,and there were unreasonable phenomena in the aspects of overdose medication,failure to monitor blood pressure as required during medication,unreasonable combination medication,compatibility taboo and so on.The compliance rate of medical results was 90.0%.Conclusion:DUE work can improve the standardization and normalization of drug evaluation.Problems and deficiencies in clinical drug use can be found,which is conducive to the continuous level improvement of rational clinical drug use.

关 键 词：非甾体抗炎药 注射用帕瑞昔布钠 药物利用评价标准 合理用药 

分 类 号：R969.3[医药卫生—药理学]